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Real-life Experience of Clinical Efficacy of Omalizumab Use in the Middle-East: Should We Also Be Concerned About Parasites?

机译:中东地区使用Omalizumab的临床疗效的现实生活经验:我们还应该关注寄生虫吗?

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摘要

Background: Omalizumab is a monoclonal anti-IgE antibody approved for the treatment of severe allergic asthma. There is increasing evidence in the literature of its usefulness in other allergic conditions such as chronic urticaria and nasal polyposis. Methods: Here in, we report a prospective case series of 52 adult patients in a tertiary university hospital, Allergy and Immunology Clinic: 36 with severe asthma, among them 6 with associated nasal polyposis, 2 with associated hypereosino-philia in the range of 25% not explained by other etiologies, and one had associated atopic dermatitis.
机译:背景:Omalizumab是一种获准用于治疗严重过敏性哮喘的单克隆抗IgE抗体。文献中越来越多的证据表明其可用于其他过敏性疾病,例如慢性荨麻疹和鼻息肉。方法:在这里,我们报告了一家三级大学医院变态反应和免疫学诊所的52位成年患者的前瞻性病例系列:36例患有严重哮喘,其中6例伴有鼻息肉病,2例伴有嗜酸性粒细胞增多症%没有由其他病因解释,并且与相关的特应性皮炎。

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