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Specific antipsychotic drugs prescribed for dementia could increase mortality

机译：开具痴呆症的特定抗精神病药可能会增加死亡率

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Elderly patients treated with specific antipsychotic drugs for dementia are at increased risk of death, according to a population-based cohort study involving 75,445 nursing home residents aged 65 or older. The results emphasize the compelling need to develop alternative treatment methods for older patients with dementia. Currently, up to a third of all elderly patients in nursing homes are treated with antipsychotic drugs. However, recently, concerns over the safety of antipsychotic drugs in the elderly have accumulated and, accordingly, the US FDA has issued advisory warnings for the use of both conventional and atypical antipsychotics in older patients. Researchers in the USA undertook the largest study involving US nursing home residents, to investigate the increased risk of mortality due to specific antipsychotic drugs: haloperidol, aripipra-zole, olanzapine, quetiapine, risperidone and ziprasidone.
机译：根据一项基于人群的队列研究，涉及75,445名65岁或65岁以上的养老院居民，老年痴呆症患者接受特殊抗精神病药物治疗的死亡风险增加。结果强调迫切需要开发针对老年痴呆患者的替代治疗方法。目前，在疗养院中，多达三分之一的老年患者接受了抗精神病药物的治疗。然而，近来，人们对抗精神病药在老年人中的安全性的担忧不断累积，因此，美国食品和药物管理局发布了针对年长患者使用常规和非典型抗精神病药的咨询警告。美国的研究人员进行了一项涉及美国疗养院居民的最大研究，以调查由于特定的抗精神病药物（氟哌啶醇，阿立哌唑，奥氮平，喹硫平，利培酮和齐拉西酮）增加的死亡风险。

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