...
首页> 外文期刊>Clinical journal of the American Society of Nephrology: CJASN >Outcomes of arteriovenous fistula creation after the fistula first initiative
【24h】

Outcomes of arteriovenous fistula creation after the fistula first initiative

机译:瘘管首次启动后动静脉瘘的形成结果

获取原文
获取原文并翻译 | 示例
           

摘要

Background and objectives The arteriovenous fistula (AVF) is the preferred hemodialysis access, but AVFfailure rate is high, and complications from AVF placement are rarely reported. There is no clear consensus on predictors of AVF patency. This study determined AVF outcomes and patency predictors at Mayo Clinic Rochester following the Fistula First Initiative. Design, setting, participants, & measurements A retrospective cohort study of AVFs placed at Mayo Clinic from January 2006 through December 2008 was performed. The AVF placement-associated primary and secondary failure rates, complications, interventions, and hospitalizations were examined. Kaplan-Meier survival curves and Cox proportional hazard models were used to determine primary and secondary patency and associated predictors. Results During this time frame, 317 AVFs were placed in 293 individual patients. The primary failure rate was 37.1% after excluding patients not initiated on hemodialysis during follow-up (n = 38) or those with indeterminate outcome (37 lost to follow-up; six died; two transplanted). Of usable AVFs, 11.4% later failed. AVF creation incurred complications and hospitalization in 21.2% and 12.3% of patients, respectively. The risk for reduced primary patency was increased by diabetes (HR, 1.54; 95% CI, 1.14 to 2.07); the risk for reduced primary and secondary patency was decreased with larger arteries (HR, 0.83; 95% CI, 0.73 to 0.94; and HR, 0.69; 95% CI, 0.56 to 0.84, respectively). Conclusions Primary failure remains a major issue in the post-Fistula First era. Complications from AVF placement must be considered when planning AVF placement. Our data demonstrate that artery size is the main predictor of AVF patency.
机译:背景和目的动静脉瘘(AVF)是首选的血液透析途径,但AVF的失败率很高,很少报道因AVF放置引起的并发症。关于AVF通畅的预测因素尚无明确共识。这项研究确定了瘘管优先行动后,在梅奥诊所罗切斯特的AVF结果和通畅性预测指标。设计,设置,参与者和测量从2006年1月至2008年12月,对梅奥诊所的AVF进行了回顾性队列研究。检查了与AVF放置相关的原发和继发失败率,并发症,干预措施和住院情况。使用Kaplan-Meier生存曲线和Cox比例风险模型确定主要和次要通畅度以及相关的预测因子。结果在这段时间内,在293例患者中放置了317枚AVF。在排除随访期间未进行血液透析的患者(n = 38)或预后不确定的患者(37例失访; 6例死亡; 2例移植)后,主要失败率为37.1%。在可用的AVF中,有11.4%之后失败了。 AVF的产生分别导致21.2%和12.3%的患者发生并发症和住院治疗。糖尿病会增加原发性通畅降低的风险(HR,1.54; 95%CI,1.14至2.07);大动脉可降低原发和继发通畅性降低的风险(HR,0.83; 95%CI,0.73至0.94; HR,0.69; 95%CI,0.56至0.84)。结论原发性失败仍然是后瘘第一时代的主要问题。计划AVF放置时,必须考虑来自AVF放置的并发症。我们的数据表明,动脉大小是AVF通畅的主要预测指标。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号