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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Preoperative localization of parathyroid adenoma with sonography and 99mTc-sestamibi scintigraphy in primary hyperparathyroidism.
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Preoperative localization of parathyroid adenoma with sonography and 99mTc-sestamibi scintigraphy in primary hyperparathyroidism.

机译：在原发性甲状旁腺功能亢进症中进行超声检查和99mTc-司他他比闪烁显像对甲状旁腺腺瘤的术前定位

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摘要

PURPOSE: To evaluate the sensitivity, specificity, and usefulness of dual-phase 99mTc-Sestamibi scintigraphy (SS) and sonography (US) of the neck, alone and in combination, as noninvasive adenoma localizing procedures in patients with primary hyperparathyroidism prior to parathyroidectomy. METHODS: We retrospectively analyzed the charts of 79 patients with parathyroid (PT) adenomas and confirmed diagnosis of hyperparathyroidism who were evaluated with SS and US prior to successful parathyroidectomy. RESULTS: Ninety-three adenomas were removed during bilateral neck exploration. SS alone showed a sensitivity of 76% and a specificity of 79% compared with 89% and 75%, respectively, for US performed after SS on the same day. Combination of the 2 procedures yielded a sensitivity of 89% and a specificity of 90%, with 22% discordant results. The differences in sensitivity and specificity between the 2 techniques alone or in combination were not statistically significant. CONCLUSIONS: No benefit was gained fromusing both SS and US for the preoperative localization of PT adenomas in patients with primary hyperparathyroidism. Each technique can be negatively affected by thyroid enlargement and nodularity. US, when performed by a skilled operator, is a reliable tool for PT adenoma localization. If the US findings are inconclusive, SS should be used.
机译：目的：评估甲状旁腺切除术前原发性甲状旁腺功能亢进患者的双阶段99mTc-Sestamibi闪烁显像（SS）和颈部超声（US）的敏感性，特异性和实用性，作为原发性甲状旁腺功能亢进患者的无创腺瘤定位程序。方法：我们回顾性分析了79例甲状旁腺（PT）腺瘤患者的病历，并确定了甲状旁腺功能亢进症的诊断，这些患者在成功进行甲状旁腺切除术之前接受了SS和US检查。结果：在双侧颈部探查中去除了93个腺瘤。单独的SS表现出76％的敏感性和79％的特异性，而同一天在SS后进行的US表现分别为89％和75％。两种方法的组合产生89％的灵敏度和90％的特异性，结果差异为22％。两种技术单独使用或组合使用时，灵敏度和特异性的差异均无统计学意义。结论：在原发性甲状旁腺功能亢进症患者中，同时使用SS和US进行PT腺瘤的术前定位均无益处。每种技术都会受到甲状腺肿大和结节的不利影响。 US由熟练的操作员执行时，是PT腺瘤定位的可靠工具。如果美国的结论尚无定论，则应使用SS。

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