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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Hemodynamic changes in hepatic artery after glucose ingestion in healthy subjects and patients with cirrhosis.
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Hemodynamic changes in hepatic artery after glucose ingestion in healthy subjects and patients with cirrhosis.

机译：健康受试者和肝硬化患者摄入葡萄糖后肝动脉血流动力学变化。

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PURPOSE: The purpose of this study was to investigate hemodynamic changes in the hepatic artery after glucose ingestion. METHODS: We used color Doppler sonography to measure hemodynamic changes in the right hepatic artery and the right portal vein in response to glucose ingestion (225 ml, 300 kcal) in 25 healthy subjects and 25 patients with cirrhosis. RESULTS: In healthy subjects, the peak systolic and end-diastolic velocities in the right hepatic artery decreased (33 +/- 3% and 53 +/- 3%) from baseline velocities measured in the fasting state. The resistance index of the right hepatic artery and the velocity in the right portal vein in these subjects significantly (p < 0.01) increased (14 +/- 2% and 32 +/- 2%) from baseline values after glucose ingestion. Glucose ingestion produced significantly (p < 0.01) smaller changes in cirrhotic patients. The maximum decrease in the peak systolic and end-diastolic velocities in the right hepatic artery were 13 +/- 2% and 25 +/- 3% from baseline velocities, and the maximum increases in the resistance index of the right hepatic artery and the velocity in the right portal vein were 6 +/- 1% and 10 +/- 3% from baseline values. CONCLUSIONS: The decrease in blood flow velocity in the right hepatic artery after glucose ingestion is presumably a homeostatic mechanism to maintain constant hepatic perfusion. This reciprocal response was reduced in cirrhotic patients.
机译：目的：本研究的目的是研究葡萄糖摄入后肝动脉的血流动力学变化。方法：我们使用彩色多普勒超声检查了25名健康受试者和25例肝硬化患者因摄入葡萄糖（225 ml，300 kcal）而引起的右肝动脉和右门静脉血流动力学变化。结果：在健康受试者中，右肝动脉的收缩和舒张末期峰值速度较空腹状态下的基线速度降低（33 +/- 3％和53 +/- 3％）。这些受试者的右肝动脉阻力指数和右门静脉速度明显（p <0.01）从葡萄糖摄入后的基线值增加（14 +/- 2％和32 +/- 2％）。在肝硬化患者中，葡萄糖摄入的变化明显较小（p <0.01）。右肝动脉的最大收缩和舒张末期速度峰值相对基线速度最大降低了13 +/- 2％和25 +/- 3％，右肝动脉和右肝动脉的阻力指数最大增加右门静脉的血流速度比基线值高6 +/- 1％和10 +/- 3％。结论：葡萄糖摄入后右肝动脉血流速度的降低可能是维持恒定肝灌注的体内平衡机制。肝硬化患者的这种相互反应减少。

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