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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Detection and differential diagnosis of hepatic masses using pulse inversion harmonic imaging during the liver-specific late phase of contrast enhancement with levovist.
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Detection and differential diagnosis of hepatic masses using pulse inversion harmonic imaging during the liver-specific late phase of contrast enhancement with levovist.

机译：在左心室造影剂增强肝脏特异性晚期期间，使用脉冲反转谐波成像检测和鉴别肝脏肿块。

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PurposeThe purpose of this study was to investigate whether late-phase pulse inversion harmonic imaging (PIHI) increases conspicuity in hepatic masses, helps to differentiate benign from malignant lesions, and demonstrates a greater number of and smaller metastatic lesions than do conventional (fundamental) sonography and helical CT.MethodsThirty patients (17 women and 13 men; age range, 35-77 years; mean age, 54 years) with known or suspected liver masses were evaluated using both fundamental sonography and contrast-enhanced PIHI during the liver-specific late phase of Levovist. The patients also underwent contrast-enhanced triphasic helical CT examinations within 1 week after sonography. In 4 of the patients, gadolinium-enhanced MRI was also performed as a part of their clinical work-up.ResultsThe increase in the lesions' conspicuity on PIHI compared with fundamental sonography was significantly greater in malignant lesions than in benign lesions (p< 0.001). An echogenic rim was observed on PIHI in 8 (53%) of 15 malignant lesions. The mean number of metastatic lesions visualized on PIHI (5.5 +/- 5.3) was significantly higher than the mean number visualized on fundamental sonography (2.5 +/- 2.1, p < 0.05). Although lesions as small as 3 mm were observed on PIHI, the mean sizes of the smallest lesions demonstrated using fundamental sonography, PIHI, and helical CT were not significantly different.ConclusionsLate-phase PIHI is a useful technique for characterizing hepatic lesions and demonstrating both a greater number of and smaller metastases. It may help to differentiate benign from malignant liver masses and may obviate unnecessary and expensive further imaging.
机译：目的本研究的目的是调查晚期脉冲反转谐波成像（PIHI）是否会增加肝脏肿块的醒目性，有助于区分良性和恶性病变，并证明与传统的（基本）超声检查相比，转移性病变的数量更多，更小方法对30例年龄在35-77岁，平均年龄54岁的肝脏已知或疑似肝脏肿块的患者（17例女性和13例男性）进行了超声检查和对比增强PIHI评估左派主义者的阶段。超声检查后的1周内，患者还接受了增强对比的三相螺旋CT检查。在4例患者中，还进行了lin增强MRI检查，作为临床检查的一部分。结果与恶性病变相比，PIHI病变的明显程度比基础超声检查明显增加，良性病变的发生率显着更高（p <0.001 ）。在15例恶性病变中，有8例（53％）在PIHI上观察到回声边缘。在PIHI上观察到的转移灶的平均数（5.5 +/- 5.3）显着高于在基础超声检查中观察到的转移灶的平均数（2.5 +/- 2.1，p <0.05）。尽管在PIHI上观察到的病变小至3 mm，但使用基本超声，PIHI和螺旋CT表现出的最小病变的平均大小没有显着差异。结论晚期PIHI是一种有用的技术，可用于表征肝病变并证明两者转移的数量更多，转移更小。它可以帮助区分良性和恶性肝脏肿块，并且可以避免不必要且昂贵的进一步成像。

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