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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Hepatic vein Doppler waveform changes in early stage (Child-Pugh A) chronic parenchymal liver disease.
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Hepatic vein Doppler waveform changes in early stage (Child-Pugh A) chronic parenchymal liver disease.

机译：慢性实质肝病早期（Child-Pugh A）的肝静脉多普勒波形变化。

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摘要

Doppler waveform changes can be found in chronic parenchymal liver disease, especially in the late stages. We investigated the contribution of Doppler ultrasound in diagnosing early-stage chronic parenchymal liver disease. In this prospective study, 30 patients who had been diagnosed with chronic liver disease (Child-Pugh class A) and 30 healthy subjects were studied. The diagnosis was confirmed with histopathologic examinations of biopsy specimens in 17 patients. The Doppler US examination of hepatic veins was performed in all the patients and healthy subjects. The Doppler US pattern was classified into three groups according to the Doppler signal characteristics: (1) type 0, triphasic waveform, the presence of a short phase of reversed flow, (2) type I, decreased amplitude of the phasic oscillations without the short phase of reversed flow, and (3) type II, complete flat waveform. Normal hepatic vein waveforms (type 0) were found in 8 patients (26.66%) and abnormal hepatic waveforms (type I + type II) in 22 patients (73.33%). The results of Doppler ultrasonography were correlated with the diagnosis of early-stage chronic parenchymal liver disease (Child-Pugh class A). In all the subjects of the control group, the Doppler waveform of hepatic veins showed the triphasic pattern (type 0). In the statistical evaluation using Fisher's exact test we observed that there was a significant difference (p < 0.05) between the control group and the patient group with respect to the presence of abnormal (type I + type II) Doppler waveform. The diagnostic accuracy in the patients who had biopsy was 76.47% and that in the patients who did not was 69.23%.
机译：多普勒波形变化可在慢性实质性肝病中发现，特别是在晚期。我们调查了多普勒超声在诊断早期慢性实质性肝病中的作用。在这项前瞻性研究中，研究了30位被诊断出患有慢性肝病（Child-Pugh A级）的患者和30位健康受试者。通过对17例活检标本进行组织病理学检查证实了该诊断。对所有患者和健康受试者进行肝静脉多普勒超声检查。根据多普勒信号特征，将多普勒超声模式分为三类：（1）0型，三相波形，存在反向逆流的短相，（2）I型，减小了相位振荡的幅度而没有短路（3）II型，完全平坦的波形。肝静脉波形正常（0型）8例（26.66％），肝波形异常（I + II型）22例（73.33％）。多普勒超声检查的结果与早期慢性实质性肝病（Child-Pugh A级）的诊断相关。在对照组的所有受试者中，肝静脉的多普勒波形均显示出三相模式（0型）。在使用Fisher精确检验的统计评估中，我们观察到对照组和患者组之间存在异常（I型+ II型）多普勒波形的显着差异（p <0.05）。活检患者的诊断准确性为76.47％，未进行活检的患者为69.23％。

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