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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Should transition zone biopsies be added to 12-core systematic biopsies of the prostate?
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Should transition zone biopsies be added to 12-core systematic biopsies of the prostate?

机译：是否应将过渡区活检添加到前列腺的12芯系统活检中？

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摘要

PURPOSE: To investigate the value of additional transition zone (TZ) biopsies following 12-core biopsies in the detection and staging of prostate cancer. METHODS: From October 2006 to March 2007, 199 transrectal sonographic (TRUS)-guided prostate biopsies (group 1) in 12 peripheral zones (PZ) were performed. Another 199 consecutive patients (group 2) underwent two TZ biopsies in addition to twelve PZ biopsies from March 2007 to July 2007. Mean prostate-specific antigen (PSA) level, prostate volume, Gleason score, and cancer detection rate of each group were compared. The anatomic distribution of prostate cancer in group 2 was also analyzed. RESULTS: Prostate cancer was detected in 76 of 199 patients (38.2%) in group 1 and 71 out of 199 patients (35.3%) in group 2. The cancer detection rate, mean PSA level, prostate volume, and Gleason score were not statistically different in the 2 groups. Cancer was detected by additional TZ biopsies alone in just one out of 71 patients (1.4%). CONCLUSION: Routine TZ biopsies following 12-core systematic biopsies are not warranted for the detection of TZ cancer because of their low additional yield.
机译：目的：研究12核心活检后其他过渡区（TZ）活检在前列腺癌的检测和分期中的价值。方法：从2006年10月至2007年3月，在12个周边区域（PZ）进行了199次经直肠超声（TRUS）引导的前列腺活检（第1组）。从2007年3月至2007年7月，除12例PZ活检外，另外199名连续患者（第2组）也进行了2次TZ活检。比较了每组的平均前列腺特异性抗原（PSA）水平，前列腺体积，格里森评分和癌症检出率。 。还分析了第2组中前列腺癌的解剖分布。结果：第1组199例患者中有76例（38.2％）检出前列腺癌，第2组199例患者中有71例（35.3％）检出前列腺癌。癌症检出率，平均PSA水平，前列腺体积和Gleason评分均无统计学意义2组不同。仅71名患者中有一名（1.4％）仅通过其他TZ活检就发现了癌症。结论：12核心系统活检后的常规TZ活检不保证检测TZ癌，因为它们的附加产率较低。

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