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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Correlation of hepatic vein Doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease.
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Correlation of hepatic vein Doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease.

机译：肝静脉多普勒波形和肝动脉阻力指数与非酒精性脂肪性肝病严重程度的相关性。

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PURPOSE: The study was conducted to evaluate the effect of various degrees of fatty infiltration in patients with nonalcoholic fatty liver disease on hepatic artery resistance index and hepatic vein waveform patterns. METHODS: After identification and grading of fatty infiltration, 60 patients and 20 normal healthy subjects were examined using color and spectral Doppler sonography. The level of fatty liver infiltration was ascertained and graded by biopsy in patients and excluded by MRI in controls. The patients were allocated to four study groups consecutively, until the required number was reached, according to infiltration level as follows: normal (group A), mild (group B), moderate (group C), and severe (group D). The hepatic vein waveforms were classified into the three following groups: triphasic, biphasic, and monophasic waveform. The hepatic artery resistance index was calculated as the mean of three different measurements. RESULTS: The incidence of monophasic and biphasic hepatic vein waveform was 2 (10%) for group B, 11 (55%) for group C, 16 (80%) for group D, and none for group A. The difference in the distribution of triphasic Doppler waveform pattern between the patients and the control group was significant (p < 0.001). Hepatic artery resistance index was 0.81 (+ or - 0.02), 0.78 (+ or - 0.03), 0.73 (+ or - 0.03), and 0.68 (+ or - 0.05), respectively, in groups A, B, C, and D and was significantly different between groups (p < 0.001). CONCLUSION: As the severity of nonalcoholic fatty infiltration increases, the incidence of abnormal hepatic vein waveforms increases and hepatic artery resistance index decreases.
机译：目的：本研究旨在评估非酒精性脂肪肝患者不同程度的脂肪浸润对肝动脉阻力指数和肝静脉波形的影响。方法：对脂肪浸润进行鉴定和分级后，使用彩色和频谱多普勒超声检查了60例患者和20例正常健康受试者。脂肪肝浸润的水平通过活检确定和分级，而对照组则不包括MRI。依次将患者分为四个研究组，直到达到所需数量为止，根据渗透水平如下：正常（A组），轻度（B组），中度（C组）和重度（D组）。肝静脉波形分为三类：三相，双相和单相波形。肝动脉阻力指数计算为三个不同测量值的平均值。结果：B组单相和双相肝静脉波形的发生率为2（10％），C组为11（55％），D组为16（80％），而A组则无。患者与对照组之间的多普勒多普勒波形图的差异显着（p <0.001）。 A，B，C和D组的肝动脉阻力指数分别为0.81（+或-0.02），0.78（+或-0.03），0.73（+或-0.03）和0.68（+或-0.05）。各组之间存在显着差异（p <0.001）。结论：随着非酒精性脂肪浸润程度的增加，肝静脉异常波形的发生率增加，肝动脉阻力指数降低。

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