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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Thalamic volume measurement in normal fetuses using three-dimensional sonography
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Thalamic volume measurement in normal fetuses using three-dimensional sonography

机译：使用三维超声检查正常胎儿的丘脑体积

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Purpose: Brain thalami are important for a wide range of sensorimotor and neuropsychiatric functions. This study was carried out to calculate normative values for thalami volume during fetal life. Methods: Fetal thalami volumes were measured using 3D ultrasound in 122 normal, singleton fetuses at 20 +0-34 +6 weeks' gestation. Virtual Organ Computer-aided AnaLysis (VOCAL) was used to obtain a sequence of six sections of each thalamus, starting from the transthalamic view of the brain at an axial plane. Thalamic contour was drawn manually. Volume contrast imaging was used to enhance image quality when needed. The volume of the thalamus distal to the transducer was also measured by a second operator in 30 randomly selected cases, blind to the measurements of the first, to calculate interobserver agreement. Results: Thalamic volume increased with gestational age, following a quadratic equation (R 2 = 0.83). There was no significant difference in volume between the right and left thalamus. The mean volume of each thalamus increased from 0.45 ml at 20 +0 weeks, to 1.39 ml at 28 +0 weeks, to 2.17 ml at 34 +0 weeks. The 95% limits of interobserver agreement for thalamic volume were -14.3% to +17.2%. Conclusions: The increase in thalamic volume with gestation can be described adequately by a quadratic equation. The moderate interobserver repeatability is attributed to the similar echogenicity between the thalamus and its surrounding structures.
机译：目的：脑部丘脑对于多种感觉运动和神经精神功能很重要。进行这项研究是为了计算胎儿生命期间沙门氏菌含量的标准值。方法：使用3D超声在妊娠20 + 0-34 +6周时对122例正常单胎胎儿进行胎儿丘脑测量。使用虚拟器官计算机辅助分析（VOCAL），从大脑在轴向平面的丘脑视图开始，获得每个丘脑的六个部分的序列。丘脑轮廓是手动绘制的。必要时，使用体积对比成像来提高图像质量。在30个随机选择的病例中，第二位操作者也测量了换能器远端丘脑的体积，而对第一个操作者的测量不了解，以计算观察者之间的一致性。结果：遵循二次方程（R 2 = 0.83），丘脑体积随胎龄增加。左右丘脑之间的体积没有显着差异。每个丘脑的平均体积从20 +0周的0.45 ml增加到28 +0周的1.39 ml，增加到34 +0周的2.17 ml。丘脑体积的观察者间协议的95％限制为-14.3％至+ 17.2％。结论：妊娠期丘脑体积的增加可以用二次方程来充分描述。观察者之间的中等重复性归因于丘脑及其周围结构之间的相似回声性。

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