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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Clinical value of carotid wave intensity analysis for differentiating nonobstructive hypertrophic cardiomyopathy from left ventricular hypertrophy secondary to systemic hypertension
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Clinical value of carotid wave intensity analysis for differentiating nonobstructive hypertrophic cardiomyopathy from left ventricular hypertrophy secondary to systemic hypertension

机译：颈动脉波强度分析对系统性高血压继发左心室肥厚与非阻塞性肥厚型心肌病的鉴别诊断价值

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摘要

Purpose.: Wave intensity (WI) is a set of new hemodynamic indexes (W1, W2, and NA) based on the calculation of (dp/dt) × (dv/dt) on any artery. We assessed the value of carotid WI analysis for differentiating nonobstructive hypertrophic cardiomyopathy (NOHCM) from left ventricular hypertrophy secondary to hypertension (LVHSH). Methods.: Nineteen NOHCM, 34 LVHSH, and 37 normal controls (NC) underwent conventional echocardiographic examination and carotid WI analysis performed with an Aloka α10 sonographic system (Alok, Tokyo, Japan) with real-time wave intensity calculation software. Results.: W1 was higher in NOHCM (11,830 ± 7,850 mmHg·m·s-3) and in LVHSH (13,670 ± 13,490 mmHg·m·s-3) than in NC (7,010 ± 3,620 mmHg·m·s-3). W2 was lower in NOHCM (850 ± 870 mmHg·m·s-3) than in LVHSH (2,310 ± 1,390 mmHg·m·s-3, p 0.01) and in NC (1,650 ± 960 mmHg·m·s-3, p 0.01). Using W2 ≤ 1,100 mmHg·m·s-3 as a threshold for differentiating NOHCM from LVHSH yielded an 84.2% sensitivity and 82.4% specificity. NA was higher in LVHSH (57.55 ± 57.82 mmHg·m·s-2) than in NOHCM (34.24 ± 13.03 mmHg·m·s-2, p 0.05) and in NC (31.67 ± 23.05 mmHg·m·s-2, p 0.05). Using NA ≤40 mmHg·m·s-2 as a threshold for differentiating NOHCM from LVHSH yielded a 63.2% sensitivity and 70.6% specificity. Conclusions.: W2 and NA indexes derived from carotid WI analysis may be helpful for differentiating NOHCM from LVHSH.
机译：目的：波强度（WI）是一组基于任何动脉上（dp / dt）×（dv / dt）的计算得出的一组新的血液动力学指标（W1，W2和NA）。我们评估了颈动脉WI分析在区分非阻塞性肥厚型心肌病（NOHCM）和高血压继发性左心室肥厚（LVHSH）中的价值。方法：19名NOHCM，34名LVHSH和37名正常对照（NC）进行了常规超声心动图检查，并使用Alokaα10超声系统（日本东京的Alok）和实时波强度计算软件进行了颈动脉WI分析。结果：NOHCM（11,830±7,850 mmHg·m·s-3）和LVHSH（13,670±13,490 mmHg·m·s-3）的W1高于NC（7,010±3,620 mmHg·m·s-3） 。 NOHCM（850±870 mmHg·m·s-3）中的W2低于LVHSH（2,310±1,390 mmHg·m·s-3，p <0.01）和NC（1,650±960 mmHg·m·s-3）中的W2较低，p ＜0.01）。使用W2≤1100 mmHg·m·s-3作为将NOHCM与LVHSH区分的阈值，可获得84.2％的灵敏度和82.4％的特异性。 LVHSH（57.55±57.82 mmHg·m·s-2）的NA高于NOHCM（34.24±13.03 mmHg·m·s-2，p <0.05）和NC（31.67±23.05 mmHg·m·s-2） ，p ＜0.05）。使用NA≤40mmHg·m·s-2作为阈值来区分NOHCM和LVHSH，可获得63.2％的灵敏度和70.6％的特异性。结论：颈动脉WI分析得出的W2和NA指数可能有助于将NOHCM与LVHSH区分开。

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