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首页> 外文期刊>Journal of Comparative Pathology >Experimental Study of the Pathogenicity of Pasteurella multocida Capsular Type B in Rabbits
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Experimental Study of the Pathogenicity of Pasteurella multocida Capsular Type B in Rabbits

机译：穆氏巴斯德氏菌荚膜B型兔致病性的实验研究

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摘要

The increased frequency of isolation of Pasteurella multocida capsular type B from rabbitries in north-western India prompted this investigation into the role of this organism in inducing disease in rabbits. Ten rabbits were divided into two groups of five animals. Group I rabbits were infected intranasally (IN) with 1 ml of inoculum containing 2 x 10(5) colony forming units/ml, while rabbits in group II were given 1 ml phosphate buffered saline IN. The rabbits in group I developed respiratory distress, increased rectal temperature and severe dyspnoea, with death occurring 24-48 h post infection. The main pathological findings were severe congestion and haemorrhage in the trachea, fibrinopurulent pneumonia, bacteraemia and septicaemia. The nasal secretions of all group I animals contained P. multocida. These observations indicate that in addition to P. multocida capsular types A and D, P. multocida capsular type B can also be highly pathogenic for rabbits. (C) 2015 Elsevier Ltd. All rights reserved.
机译：从印度西北部的家禽中分离出多杀性巴斯德氏菌荚膜B型荚膜的频率增加，促使人们对该生物体在诱发兔子疾病中的作用进行了调查。将十只兔子分成两组，每组五只动物。第一组兔子经鼻内（IN）感染1 ml含2 x 10（5）集落形成单位/ ml的接种物，而第二组兔子则被给予1 ml磷酸盐缓冲盐水IN。第一组的兔子出现呼吸窘迫，直肠温度升高和严重呼吸困难，感染后24-48小时死亡。主要病理结果是气管严重充血和出血，纤维化脓性肺炎，菌血症和败血病。所有第一组动物的鼻分泌物中都含有多杀性巴氏杆菌。这些观察结果表明，除了A型和D型多杀青霉荚膜荚膜，B型多杀青霉荚膜荚膜对兔子也具有高致病性。 （C）2015 Elsevier Ltd.保留所有权利。

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