首页> 外文期刊>Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia >Giant cell polymyositis associated with myasthenia gravis and thymoma
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Giant cell polymyositis associated with myasthenia gravis and thymoma

机译:重症肌无力和胸腺瘤相关的巨细胞多肌炎

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We report a case of a 40-year-old woman who developed generalized muscle weakness over a period of 2 months. Physical examination revealed palpable masses in her arms and hands. Serum creatine kinase levels were elevated. Electromyography showed myopathic changes and 3 Hz repetitive nerve stimulation revealed a decremental pattern on repetitive nerve stimulation. Muscle MRI demonstrated increased signal intensity in the biceps brachii on T1-weighted images. Chest CT scan showed a mediastinal mass suggestive of thymoma. Muscle biopsy revealed giant cell polymyositis. The patient was treated with cholinesterase inhibitors and corticosteroids with improvement of strength, and subsequently underwent thymectomy followed by radiotherapy. (C) 2014 Elsevier Ltd. All rights reserved.
机译:我们报告了一例40岁的女性,在2个月的时间内出现全身性肌肉无力。体格检查发现她的手臂和手中有明显的肿块。血清肌酸激酶水平升高。肌电图显示肌病变化,3 Hz重复神经刺激显示重复神经刺激呈递减模式。肌肉MRI显示在T1加权图像上肱二头肌的信号强度增加。胸部CT扫描显示有纵隔肿块提示胸腺瘤。肌肉活检显示巨细胞多肌炎。该患者接受胆碱酯酶抑制剂和皮质类固醇激素治疗,强度得到改善,随后接受胸腺切除术,然后放疗。 (C)2014 Elsevier Ltd.保留所有权利。

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