首页> 外文期刊>Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia >Therapeutic hypothermia for severely head-injured patients with acute subdural haematoma.
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Therapeutic hypothermia for severely head-injured patients with acute subdural haematoma.

机译:急性硬脑膜下血肿严重颅脑损伤患者的治疗性体温过低。

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The benefit of hypothermia therapy for severely head-injured patients has been a matter of controversy, and the appropriate indications have yet to be clarified. The authors have employed mild hypothermia to treat severe acute subdural haematoma (ASDH) patients postoperatively as a means of controlling intracranial pressure. The potential roles of hypothermia in the treatment of severe ASDH patients are discussed. Between 1997 and 2000, 18 ASDH patients with a GCS on admission of 6 or less were treated by haematoma evacuation with postoperative mild hypothermia. The efficacy of hypothermia was evaluated retrospectively by comparing the outcome of these 18 patients with that of 15 ASDH patients who underwent surgery without postoperative hypothermia between 1993 and 1996. Hypothermia significantly increased both the survival and favorable outcome rates of the 18 ASDH patients, compared with the historic controls. However, the benefit of hypothermia was seen only in ASDH patients without associated cerebral contusion, and no significant protective effect of hypothermia was seen in ASDH patients with contusion. Hypothermia may be a useful postoperative therapeutic modality for severe ASDH without concomitant cerebral contusion. A future prospective study is warranted to support the conclusions of this retrospective study.
机译:亚低温疗法对重度颅脑损伤患者的益处一直存在争议,而且尚无明确的适当适应症。作者采用轻度低温治疗术后严重的急性硬脑膜下血肿(ASDH)患者,作为控制颅内压的一种手段。讨论了低温对重度ASDH患者的治疗作用。在1997年至2000年之间,对18例入院GCS为6或更少的ASDH患者进行了手术后轻度亚低温的血肿清除术治疗。通过比较这18例患者与1993年至1996年间未经术后低温手术的15例ASDH患者的结局,对低温的疗效进行了回顾性评估。与历史控制。然而,仅在没有伴有脑挫伤的ASDH患者中看到了低温治疗的益处,而在患有挫伤的ASDH患者中没有发现明显的低温保护作用。对于没有伴有脑挫伤的严重ASDH,低体温可能是一种有用的术后治疗方法。将来有必要进行前瞻性研究以支持该回顾性研究的结论。

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