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首页> 外文期刊>Clinical Biochemistry >Lactase persistence versus lactose intolerance: Is there an intermediate phenotype?
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Lactase persistence versus lactose intolerance: Is there an intermediate phenotype?

机译:乳糖酶持久性与乳糖不耐受性:是否存在中间表型?

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摘要

Background: According to the prevailing theory about the genetic background to lactose intolerance, there are three genotypes but only two adult physiological phenotypes: lactase persistence in individuals with the CT and TT genotypes and lactase non-persistence in individuals with the CC genotype. However, analysis of lactase activity from intestinal biopsies has revealed three distinct levels of activity, suggesting that an intermediate physiological phenotype may exist.
机译:背景:根据关于乳糖不耐症的遗传背景的流行理论,存在三种基因型,但只有两种成人生理表型:具有CT和TT基因型的个体中的乳糖酶持续性和具有CC基因型的个体中的乳糖酶非持续性。但是,对肠道活检组织中乳糖酶活性的分析揭示了三种不同的活性水平,表明可能存在中间生理表型。

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