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首页> 外文期刊>Journal of Clinical Epidemiology >Prevalence of morbidity and multimorbidity in elderly male populations and their impact on 10-year all-cause mortality: The FINE study (Finland, Italy, Netherlands, Elderly).
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Prevalence of morbidity and multimorbidity in elderly male populations and their impact on 10-year all-cause mortality: The FINE study (Finland, Italy, Netherlands, Elderly).

机译：FINE研究（芬兰，意大利，荷兰，老年人）在老年男性人群中的发病率和多发病率及其对10年全因死亡率的影响。

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Older males are known to carry, more likely than younger people, one or more chronic diseases with an expected impact on mortality. This study was aimed at identifying the relationship of prevalent chronic diseases in elderly populations of different countries with all-cause mortality. Men aged 65-84 from defined areas were enrolled in Finland (N=716), the Netherlands (N=887) and Italy (N=682). They were survivors of cohorts studied for 25 years within the Seven Countries Study. Major chronic diseases were diagnosed at entry. Ten-year follow-up for mortality was completed. Entry prevalence of selected chronic diseases was higher in Finland (56%) than in Italy (51%) and the Netherlands (44%). Ten-year age-adjusted death rates from all causes were higher in Finland (565 per 1000) and lower in the Netherlands (478 per 1000) and Italy (445 per 1000). The absolute risk of death related to chronic disease was high in the three countries, but was higher in Finland than in the Netherlands and Italy. The most lethal condition was stroke, with 10-year death rates of 806 per 1000 in Finland and 707 and 729 per 1000 in the Netherlands and Italy, respectively. The relative risk of all-cause mortality for a set of seven chronic diseases (coronary heart disease, heart failure, claudicatio intermittens, cerebrovascular accidents, diabetes, COPD and cancer) adjusted by age, other diseases and cohort was less than two for each condition, except cerebrovascular accidents in the Netherlands (RR 2.20). In general, relative risk was higher in Finland, intermediate in the Netherlands and lower in Italy, where only cerebrovascular accidents, intermittent claudication, diabetes and the presence of any chronic condition had a significant relative risk. About one third of men had one chronic disease, and between 10% and 15% had two diseases. The coexistence of any two or three chronic conditions was associated with a relative risk of 2 or more in Finland and the Netherlands and less than 2 in Italy. In these elderly men prevalent morbidity and comorbidity was relatively common and it explained a large proportion of excess in all-cause mortality in 10 years of follow-up.
机译：已知年长的男性比年轻人更容易携带一种或多种慢性病，预计会对死亡率产生影响。这项研究旨在确定不同国家老年人口流行的慢性疾病与全因死亡率的关系。芬兰（N = 716），荷兰（N = 887）和意大利（N = 682）招募了来自特定地区的65-84岁男性。他们是在“七个国家”研究中研究了25年的同类研究的幸存者。入境时诊断出主要的慢性疾病。死亡率十年追踪已经完成。芬兰（56％）的某些慢性病的进入患病率高于意大利（51％）和荷兰（44％）。各种原因的十年年龄调整后死亡率在芬兰较高（565/1000），在荷兰（478/1000）和意大利（445/1000）较低。在这三个国家中，与慢性病有关的绝对死亡风险很高，但在芬兰高于荷兰和意大利。最致命的疾病是中风，芬兰的10年死亡率为806/1000，荷兰和意大利的10年死亡率分别为707和729/1000。根据年龄，其他疾病和队列调整的七种慢性疾病（冠心病，心力衰竭，间断性间断，脑血管意外，糖尿病，COPD和癌症）中，全因死亡率的相对风险小于两个，荷兰的脑血管意外除外（RR 2.20）。通常，相对风险在芬兰较高，在荷兰为中级，在意大利较低，在这些地区，只有脑血管意外，间歇性lau行，糖尿病和任何慢性病的存在才具有明显的相对风险。大约三分之一的男性患有一种慢性疾病，而10％至15％的男性患有两种疾病。在芬兰和荷兰，两种或三种慢性病的并存与相对危险度为2或更高，在意大利小于2。在这些老年男性中，普遍的发病率和合并症相对普遍，这解释了在10年的随访中，全因死亡率有很大一部分过高。

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