Clinical applications of therapeutic apheresis.

Balogun RA; Kaplan A; Ward DM; Okafor C; Burns TM; Torloni AS; Macik BG; Abdel Rahman EM

首页> 外文期刊>Journal of clinical apheresis. >Clinical applications of therapeutic apheresis.

【24h】

Clinical applications of therapeutic apheresis.

机译：治疗性血液分离的临床应用。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The vast majority of the renal indications for plasma exchange are related to immunoglobulin removal. Immunoglobulins, especially IgG, have a relatively long half-life. Thus in antibody-mediated disease, there could be persistence of significant amounts of antibody in the circulation despite cessation of antibody production. The aim of plasma exchange is to significantly reduce circulating antibodies. Removal of the circulating antibodies constitutes the rationale for using plas-mapheresis to treat antibody-associated glomeruloneph-ritis (GN). Although small molecular weight substances are removed by plasma exchange, their large volume of distribution and short half-lives make plasma exchange an inefficient means of extracorporeal removal of these substances. For instance, some complement proteins have a half-life of 2 days.

机译：血浆置换的绝大多数肾脏适应症与免疫球蛋白的去除有关。免疫球蛋白，尤其是IgG，具有相对较长的半衰期。因此，在抗体介导的疾病中，尽管抗体生产停止，循环中仍可能存在大量抗体。血浆置换的目的是显着减少循环抗体。去除循环中的抗体构成了使用血浆置换术治疗与抗体相关的肾小球肾炎（GN）的原理。尽管通过血浆交换除去了小分子量物质，但是它们的大量分布和短的半衰期使血浆交换成为体外去除这些物质的低效手段。例如，某些补体蛋白的半衰期为2天。

著录项

来源
《Journal of clinical apheresis.》 |2010年第5期|共15页
作者
Balogun RA; Kaplan A; Ward DM; Okafor C; Burns TM; Torloni AS; Macik BG; Abdel Rahman EM;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词

相似文献

外文文献
中文文献
专利

1. Guidelines on the use of therapeutic apheresis in clinical practice--evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis. [J] . Szczepiorkowski ZM, Winters JL, Bandarenko N, Journal of clinical apheresis. . 2010,第3期

机译：在临床实践中使用治疗性血液分离术的指南-美国Apheresis协会Apheresis应用委员会的基于证据的方法。
2. Guidelines on the use of therapeutic apheresis in clinical practice: evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis. [J] . Szczepiorkowski ZM, Bandarenko N, Kim HC, Journal of clinical apheresis. . 2007,第3期

机译：在临床实践中使用治疗性单采血液疗法的指南：美国Apheresis协会Apheresis应用委员会的循证方法。
3. The new approach to assignment of ASFA categories--introduction to the fourth special issue: clinical applications of therapeutic apheresis. [J] . Szczepiorkowski ZM, Shaz BH, Bandarenko N, Journal of clinical apheresis. . 2007,第3期

机译：分配ASFA类别的新方法-第四期特刊简介：治疗性血液分离术的临床应用。
4. POTENT LONG-ACTING FORMS OF POLYETHYLENE GLYCOL CONJUGATED PROTEIN THERAPEUTICS AND THEIR CLINICAL APPLICATIONS [C] . Pascal Bailon, George K. Ehrtich Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：聚乙二醇共轭蛋白疗法的强效长效型及其临床应用
5. Microfluidic Methods for Generating Clinical-Scale Quantities of Uniform Fine Emulsions for Applications in Site-Specific Therapeutics. [D] . Bardin, David. 2013

机译：微流控方法，用于产生临床规模的均匀细乳液，用于特定部位的治疗学。
6. Hypoxia in Breast Cancer—Scientific Translation to Therapeutic and Diagnostic Clinical Applications [O] . Ying Zhang, Hongyi Zhang, Minghong Wang, 2021

机译：乳腺癌缺氧 - 科学翻译给治疗和诊断临床应用
7. Infection Diseases and Malignant Tumors: Therapeutic Guidelines and Clinical Pharmacology 5. Appropriate Use of Antineoplastic Agent: Clinical Application Base on Pharmacokinetics: Pharmacokinetics, Therapeutic Drug Monitoring (TDM) [O] . NORIFUMI MORIKAWA 2004

机译：感染疾病和恶性肿瘤：治疗准则和临床药理学5.适当使用抗肿瘤剂：药代动力学临床应用基础：药代动力学，治疗药物监测（TDM）

Clinical applications of therapeutic apheresis.

摘要

著录项

相似文献

相关主题

期刊订阅