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首页> 外文期刊>Journal of computer assisted tomography >Solitary Pulmonary Nodules: A Comparative Study Evaluated with Contrast-Enhanced Dynamic MR Imaging and CT.
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Solitary Pulmonary Nodules: A Comparative Study Evaluated with Contrast-Enhanced Dynamic MR Imaging and CT.

机译：肺部孤立性结节：对比研究评估动态增强磁共振成像和CT。

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OBJECTIVE:: The aim of this prospective study was to compare the diagnostic performances of dynamic MR imaging and CT for the differentiation of benign and malignant solitary pulmonary nodules (SPNs). METHODS:: Eighty-one patients with SPNs (32 malignant, 49 benign) underwent dynamic MR imaging (n = 31), dynamic CT (n = 27), or both (n = 23). The degree of peak enhancement of benign and malignant SPNs was compared on both dynamic MR imaging and CT. Receiver operating characteristic (ROC) analysis was performed to compare the diagnostic performances of dynamic MR imaging and CT. RESULTS:: The malignant SPNs revealed significantly greater degrees of peak enhancement on dynamic MR imaging (mean +/- SD [p%SI] 131.2 +/- 46.1 versus 54.2 +/- 45.3; range [p%SI] 82.6-260.0 versus -0.7-171.7; P < 0.0001) and CT (mean +/- SD [DMI] 37.8 +/- 15.1 versus 17.9 +/- 21.8; range [DMI] 14.1-68.2 versus -5.4-107.6; P = 0.0004). Although dynamic MR imaging was somewhat superior to dynamic CT, the diagnostic performances of the 2 modalities based on ROC analysis were not statistically significant. CONCLUSIONS:: Dynamic MR imaging and CT seem to be equally well suited for the differentiation between benign and malignant SPNs.
机译：目的：这项前瞻性研究的目的是比较动态MR成像和CT对良性和恶性孤立性肺结节（SPN）的诊断性能。方法：81例SPN患者（32例恶性，49例良性）接受了动态MR成像（n = 31），动态CT（n = 27）或两者（n = 23）。在动态MR成像和CT上都比较了良性和恶性SPN的峰增强程度。进行接收器工作特性（ROC）分析以比较动态MR成像和CT的诊断性能。结果：恶性SPNs在动态MR成像上显示出明显更高的峰值增强程度（平均值+/- SD [p％SI] 131.2 +/- 46.1与54.2 +/- 45.3;范围[p％SI] 82.6-260.0与-0.7-171.7; P ＜0.0001）和CT（平均+/- SD [DMI] 37.8 +/- 15.1对17.9 +/- 21.8;范围[DMI] 14.1-68.2对-5.4-107.6; P ＝ 0.0004）。尽管动态MR成像在某种程度上优于动态CT，但基于ROC分析的两种方式的诊断性能在统计学上并不显着。结论：动态MR成像和CT似乎同样适用于良性和恶性SPN的区分。

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