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首页> 外文期刊>Journal of computer assisted tomography >Diffusion tensor MR imaging in pediatric head trauma.
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Diffusion tensor MR imaging in pediatric head trauma.

机译：弥散张量磁共振成像在小儿头部创伤中的应用。

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PURPOSE: We propose to investigate the fractional anisotropy (FA) values in pediatric patients with closed head trauma and correlate them with the initial Glasgow Coma Scale (GCS). MATERIALS AND METHODS: A retrospective evaluation of 24 pediatric patients (15 men, 9 women; mean age, 13 years; range, 2-18 years) who underwent both unenhanced head computed tomography and cerebral magnetic resonance imaging (MRI), including the tensor diffusion sequence, within 30 days of the incident. Twenty-two atraumatic control patients (9 men, 13 women; mean age, 9 years; range, 4-17 years) were randomly selected from the records of the radiology department within the same period. Fractional anisotropy measurements were taken from each of 6 major white matter volumes. Data extracted from the record of each subject included GCS, initial head computed tomographic results, and length of hospital stay. Kruskal-Wallis and t tests were used for statistical evaluation. RESULTS: The mean acute score on the GCS was 9.7 +/- 5.Mean duration of hospitalization days was 8.7 +/- 10. Statistically significant differences in mean FA values between trauma and control subjects were noted in corpus callosum. Trauma patients with positive findings on MRI and with GCS less than 10 also had lower FA values than patients with GCS greater than 10 and patients who had normal MRI findings. There was a negative correlation between time to discharge and FA values. CONCLUSIONS: In pediatric head trauma, MRI diffusion FA measurements can show abnormalities despite normal-appearing brain MRI findings. Larger investigations are required to verify the stability of correlations.
机译：目的：我们建议调查闭合性颅脑外伤患儿的分数各向异性（FA）值，并将其与初始格拉斯哥昏迷量表（GCS）相关联。材料与方法：回顾性评估了24例接受了无增强的头颅计算机断层扫描和脑磁共振成像（MRI）（包括张量）的儿科患者（男15例，女9例;平均年龄13岁;范围2-18岁）。事件发生后30天内的扩散顺序。在同一时期从放射科的记录中随机选择了22名无创伤对照患者（男9例，女13例;平均年龄9岁;范围4-17岁）。从6个主要白质体积中的每一个进行分数各向异性测量。从每个受试者的记录中提取的数据包括GCS，初始头部计算机断层扫描结果和住院时间。使用Kruskal-Wallis和t检验进行统计评估。结果：在GCS上的平均急性评分为9.7 +/-5。平均住院天数为8.7 +/-10。在体中，创伤患者和对照组之间的平均FA值在统计学上有显着差异。 MRI阳性且GCS小于10的创伤患者的FA值也低于GCS大于10和MRI正常的患者。放电时间与FA值之间呈负相关。结论：在小儿头部外伤中，尽管脑部MRI表现正常，MRI弥散FA测量仍可显示异常。需要进行更大的研究来验证相关性的稳定性。

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