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首页> 外文期刊>Journal of computer assisted tomography >Two-phase computed tomography study of warthin tumor of parotid gland: differentiation from other parotid gland tumors and its pathologic explanation.
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Two-phase computed tomography study of warthin tumor of parotid gland: differentiation from other parotid gland tumors and its pathologic explanation.

机译：腮腺warthin肿瘤的两阶段计算机断层扫描研究：与其他腮腺肿瘤的区别及其病理学解释。

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摘要

The objective of this study was to define the radiological characteristics of 2-phase computed tomography (CT) of parotid gland Warthin tumors (WTs) with a pathologic basis for these findings.We prospectively enrolled 116 patients with parotid gland tumor who underwent preoperative 2-phase CT scans(scanning delays of 30 and 120 seconds). The attenuation changes and enhancement patterns were analyzed according to pathology. We also evaluated size-matched samples of WTs and pleomorphic adenoma by staining CD31, vascular endothelial growth factor-receptor 2, collagen IV, and smooth muscle actin.Computed tomography numbers in WTs were significantly higher than those in other tumors in early-phase scans and lower in delayed scans. Pathologically, CD31(+) blood vessel area was significantly higher in WTs than in pleomorphic adenomas. In addition, WTs had an extensive capillary network and many leaky blood vessels.The enhancement pattern of early fill-in and early washout is the typical finding of WTs on 2-phase CT scans, which may be attributed pathologically to abundant blood vessel and extensive capillary network.
机译：这项研究的目的是定义腮腺Warthin肿瘤（WTs）的2期计算机断层扫描（CT）的放射学特征，并为这些发现提供病理基础。我们前瞻性招募了116例接受了2术前腮腺肿瘤的患者。相位CT扫描（扫描延迟为30和120秒）。根据病理分析衰减变化和增强方式。我们还通过对CD31，血管内皮生长因子受体2，胶原蛋白IV和平滑肌肌动蛋白染色来评估WTs和多形性腺瘤的大小匹配样本。在早期扫描中，WTs的计算机断层扫描数量显着高于其他肿瘤并降低延迟扫描的速度。病理上，WTs中的CD31（+）血管面积显着高于多形性腺瘤。此外，野生型具有广泛的毛细血管网络和许多渗漏的血管。早期填充和早期冲洗的增强模式是两相CT扫描中典型的野生型发现，这在病理上可归因于丰富的血管和广泛的毛细血管网。

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