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The effect of the virtual monochromatic spectral imaging for the metallic artifact and the pulmonary nodule detection

机译：虚拟单色光谱成像对金属伪影和肺结节检测的影响

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OBJECTIVES: This study aimed to evaluate whether dual-energy computed tomography can reduce metal artifacts and improve detection of pulmonary nodules. METHODS: Twelve simulated nodules were randomly placed inside a chest phantom with a pacemaker. Then, dual-energy computed tomography was performed, and 5 virtual monochromatic images at 40, 50, 65, 100, and 140 keV were reconstructed with 5-and 0.625-mm slice thicknesses. Two independent observers assessed the metal artifact (3-point scale from 1, none, to 3, severe) and detection of the nodule (5-point scale from 1, definitely absent, to 5, definitely present). Statistical analysis was performed with a P value of less than 0.01 (0.05/5). RESULTS: With both slice thicknesses, the metallic artifact increased at 40 or 50 keV and decreased at 100 or 140 keV relative to that at 65 keV (P < 0.01). The nodule detection score was not significantly different between each kiloelectron volt level with the 0.625-mm slice thickness; however, the score was significantly worse at 40 keV compared to 65 keV (P < 0.01) with the 5-mm slice thickness. CONCLUSIONS: High monochromatic energy images can reduce metal artifacts without a change in nodule detection score. Low monochromatic energy images increase metal artifacts and worsen nodule detection in thick slices.
机译：目的：本研究旨在评估双能计算机断层扫描是否可以减少金属伪影并改善肺结节的检测。方法：用起搏器将十二个模拟结节随机置于胸模内。然后，执行双能计算机断层扫描，并以5和0.625毫米的切片厚度重建40个，50、65、100和140 keV的5个虚拟单色图像。两名独立的观察者评估了金属伪影（3点标度，从1无到3，严重）和结节的检测（5点标度从1，无到5，肯定存在）。 P值小于0.01（0.05 / 5）进行统计分析。结果：相对于65 keV，在两种切片厚度下，金属伪影在40或50 keV时增加，在100或140 keV时减少（P <0.01）。切片厚度为0.625mm时，每千伏电子水平的结节检测得分无显着差异。然而，在40 keV时，该分数明显低于切片厚度为5 mm的65 keV（P <0.01）。结论：高单色能量图像可以减少金属伪影，而结节检测分数不变。低单色能量图像会增加金属伪影，并使厚切片中的结节检测变差。

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