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首页> 外文期刊>Journal of computer assisted tomography >Comparison of RECIST, mRECIST, and choi criteria for early response evaluation of hepatocellular carcinoma after transarterial chemoembolization using drug-eluting beads
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Comparison of RECIST, mRECIST, and choi criteria for early response evaluation of hepatocellular carcinoma after transarterial chemoembolization using drug-eluting beads

机译：RECIST，mRECIST和Choi标准用于使用药物洗脱珠子经动脉化学栓塞后肝细胞癌早期反应评估的比较

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摘要

OBJECTIVE: To determine appropriate imaging criteria for early response evaluation in patients with hepatocellular carcinoma treated with transarterial chemoembolization (TACE) using drug-eluting beads. METHODS: Seventy-six patients who underwent TACE with drug-eluting beads as a first-line treatment were included. Responses at 1 month after treatment were evaluated by comparing contrast-enhanced computed tomography or magnetic resonance imaging performed before TACE. Evaluations were performed according to Response Evaluation Criteria in Solid Tumors (RECIST), modified RECIST (mRECIST), and Choi criteria. Correlation with progression-free survival (PFS) was compared using the Kaplan-Meier method and log-rank test. RESULTS: Modified RECIST yielded a significant difference in PFS across the different response categories (P < 0.01); the Choi criteria exhibited a satisfactory difference in PFS, although the number of nonresponder patients was small (n = 5 [8.6%]). CONCLUSION: Application of mRECIST criteria at the 1-month follow-up computed tomography may be a reliable early predictor of outcome response in patients with hepatocellular carcinoma treated with TACE using drug-eluting beads.
机译：目的：确定使用药物洗脱珠粒经肝动脉化疗栓塞（TACE）治疗的肝细胞癌患者早期反应评估的适当影像学标准。方法：76例接受TACE治疗的患者均接受药物洗脱珠作为一线治疗。通过比较TACE前进行的对比增强计算机断层扫描或磁共振成像评估治疗后1个月的反应。根据实体瘤反应评估标准（RECIST），改良的RECIST（mRECIST）和Choi标准进行评估。使用Kaplan-Meier方法和对数秩检验比较了与无进展生存期（PFS）的相关性。结果：改良的RECIST在不同反应类别之间的PFS有显着差异（P <0.01）; Choi标准在PFS方面显示出令人满意的差异，尽管无反应的患者人数很少（n = 5 [8.6％]）。结论：在1个月的随访计算机体层摄影术中应用mRECIST标准可能是使用药物洗脱珠粒经TACE治疗的肝细胞癌患者可靠的早期预后指标。

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