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Campylobacter species in health, gingivitis, and periodontitis.

机译:在健康,牙龈炎和牙周炎中存在弯曲杆菌。

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At least seven Campylobacter species have been identified from subgingival sites. Campylobacter rectus has been implicated as a periodontal pathogen; however, association with periodontal infections of other Campylobacter species, especially the newly described Campylobacter showae, is unclear. This study examined which Campylobacter species were associated with periodontal health and disease. Subgingival Campylobacter species from initial and established periodontitis were compared with species from periodontally healthy subjects, including subjects with gingivitis. Campylobacter species were isolated on selective media and identified by whole-cell protein profiles (SDS-PAGE). Except for C. rectus, Campylobacter levels were frequently below the detection limit (2-5% of the microbiota) of non-selective culture methods. C. rectus and C. showae, including Campylobacter X, were found more frequently and in higher levels from diseased than from healthy periodontal sites. C. gracilis was the dominant Campylobacter species found in relatively shallow pockets; however, its presence was unrelated to periodontal health or disease. C. concisus was isolated in higher proportions from relatively shallow and healthy sites, compared with deeper pockets. C. curvus was unrelated to periodontal health or disease. Analysis of the study data confirmed the relationship of C. rectus with diseased subgingival sites and indicated that C. showae may also be associated with periodontal disease.
机译:从牙龈下部位至少鉴定出七个弯曲杆菌种。直弯弯曲杆菌被认为是牙周病原体。然而,尚不清楚与其他弯曲杆菌属,尤其是新近描述的弯曲杆菌属的牙周感染是否相关。这项研究检查了哪些弯曲杆菌与牙周健康和疾病有关。将来自最初和确定的牙周炎的龈下弯曲杆菌属物种与来自包括牙龈炎的受试者在内的牙周健康受试者的物种进行比较。在选择性培养基上分离弯曲杆菌属物种,并通过全细胞蛋白质谱(SDS-PAGE)进行鉴定。除直肌梭状芽孢杆菌外,弯曲杆菌水平经常低于非选择性培养方法的检出限(微生物群的2%至5%)。与健康牙周部位相比,患病的直肌弯曲杆菌和隐性弯曲杆菌(包括弯曲杆菌X)的发病率更高且水平更高。细小弯曲杆菌是在相对浅的口袋中发现的主要弯曲杆菌种。但是,它的存在与牙周健康或疾病无关。与较深的口袋相比,圆锥形锥虫从相对较浅且健康的地方隔离的比例更高。弯曲弯曲杆菌与牙周健康或疾病无关。对研究数据的分析证实了直肌梭菌与患牙龈下部位的关系,并表明昭哥梭菌也可能与牙周疾病有关。

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