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首页> 外文期刊>Journal of drugs in dermatology: JDD >Treatment of a symptomatic dermatofibroma with fractionated carbon dioxide laser and topical corticosteroids
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Treatment of a symptomatic dermatofibroma with fractionated carbon dioxide laser and topical corticosteroids

机译：二氧化碳激光和局部皮质类固醇激素治疗有症状的皮肤纤维瘤

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摘要

Dermatofibromas are benign skin lesions that may be treated if symptomatic or for cosmetic concerns. We present a case of an African American woman with an enlarging, pruritic dermatofibroma on the thigh that was treated with fractionated carbon dioxide (CO2) laser three times approximately 5 weeks apart. Between laser treatments, topical corticosteroids were applied to the lesion for a total of 13 weeks. The dermatofibroma completely flattened and became asymptomatic within 1 month after the final laser treatment. We hypothesize that the fractionated CO2 laser ablated a portion of the stromal component of the lesion and introduced microscopic channels that facilitated deeper penetration of the topical corticosteroids into the lesion. This is the first reported case demonstrating the successful treatment of a symptomatic dermatofibroma using combination therapy with fractionated CO2 laser and topical corticosteroids.
机译：皮肤纤维瘤是良性皮肤病变，如果有症状或出于美容目的可以治疗。我们介绍了一例非洲裔美国妇女的大腿上扩大的瘙痒性皮肤纤维瘤，接受分次二氧化碳（CO2）激光治疗，相隔约5周，进行了三次治疗。在两次激光治疗之间，将局部皮质类固醇激素用于病变部位共13周。最终的激光治疗后1个月内，皮肤纤维瘤完全变平并无症状。我们假设分馏的CO2激光烧蚀了病变的一部分基质成分，并引入了有助于局部皮质类固醇更深地渗透到病变中的微观通道。这是首次报道的病例，证实了结合分馏CO2激光和局部糖皮质激素联合治疗成功治疗症状性皮肤纤维瘤。

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