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首页> 外文期刊>Journal of drugs in dermatology: JDD >The 'Smile-and-Fill' Injection Technique: A Dynamic Approach to Midface Volumization
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The 'Smile-and-Fill' Injection Technique: A Dynamic Approach to Midface Volumization

机译：“微笑和填充”注入技术：动态处理中间面体积

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摘要

Injectable poly-L-lactic acid (PLLA) is a biodegradable, biocompatible, synthetic polymer that acts as a scaffold to promote collagen formation and is FDA-approved for the correction of facial lipoatrophy in patients with human immunodeficiency virus (HIV) infection. The safety and efficacy of injectable PLLA for the treatment of HIV-associated facial lipoatrophy has been demonstrated in clinical studies and is accompanied by improvement in patient quality of life. Volumization of the mid-face is regarded as complex. The importance of respecting patient mid-face differences at rest and in motion was highlighted in a study that demonstrated effectiveness of silicone microdroplets (0.01 mL) in a depot manner to treat HIV patients with facial lipoatrophy. One of the challenges of facial volume rejuvenation with these techniques is preserving and enhancing dynamic facial movements after treatment. To address this challenge, we developed an injection technique termed "smile-and-fill." In this case series, we describe three patients treated by this technique to restore the malar aspect of the mid-face with improvement several months post-treatment.
机译：注射用聚L-乳酸（PLLA）是一种可生物降解的，生物相容性的合成聚合物，可充当支架来促进胶原蛋白的形成，并获得FDA批准，可纠正人免疫缺陷病毒（HIV）感染患者的面部脂肪萎缩。在临床研究中已经证明了可注射的PLLA用于治疗HIV相关的面部脂肪萎缩的安全性和有效性，并伴随着患者生活质量的改善。中脸的肿胀被认为是复杂的。一项研究强调了尊重患者在休息和运动时面部中间差异的重要性，该研究表明硅油微滴（0.01 mL）以长效方式有效治疗患有面部脂肪萎缩的HIV患者。用这些技术使面部体积恢复年轻化的挑战之一是保持和增强治疗后面部的动态运动。为了应对这一挑战，我们开发了一种称为“微笑和填充”的注射技术。在本病例系列中，我们描述了三名接受此技术治疗的患者，这些患者在治疗后数月内得到了改善，从而恢复了中脸的黄斑部。

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