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首页> 外文期刊>Journal of cutaneous medicine and surgery >Successful treatment of localized pyoderma gangrenosum with topical pimecrolimus
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Successful treatment of localized pyoderma gangrenosum with topical pimecrolimus

机译:吡美莫司局部治疗成功治疗局部坏疽性脓皮病

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摘要

Pyoderma gangrenosum (PG) is an immune-mediated skin disease characterized by rapidly progressive, painful ulcers that may result in considerable scarring.1 It may occur as an isolated cutaneous phenomenon or in association with a variety of chronic inflammatory disorders, such as rheumatoid arthritis, inflammatory bowel diseases, connective tissue diseases, chronic active hepatitis, monoclonal gammopafhy, hematologic malignancies, or other miscellaneous conditions. Clinically, PG is classified into ulcerative, pustular, bullous, and vegetative types.2 The diagnosis is clinical and often one of exclusion because histopathology is not specific. It is essential to rule out other conditions, especially infections, before treatment is started.
机译:坏疽性脓皮病(PG)是一种免疫介导的皮肤病,其特征是快速进行性,疼痛性溃疡,可能导致相当大的疤痕.1它可能以孤立的皮肤现象或与多种慢性炎症性疾病如类风湿性关节炎相关,炎症性肠病,结缔组织病,慢性活动性肝炎,单克隆丙种球蛋白过多,血液系统恶性肿瘤或其他各种疾病。在临床上,PG分为溃疡型,脓疱型,大疱性和营养型。2诊断是临床的,并且通常由于组织病理学不明确而被排除在诊断之外。在开始治疗之前,必须排除其他情况,尤其是感染。

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