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首页> 外文期刊>Journal of cutaneous pathology >Secondary syphilis with an interstitial granuloma annulare-like histopathologic pattern.
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Secondary syphilis with an interstitial granuloma annulare-like histopathologic pattern.

机译：继发性梅毒伴间质性肉芽肿环状样组织病理模式。

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摘要

A granulomatous tissue response may be observed in untreated, long-standing lesions of secondary syphilis. In addition to poorly defined granulomatous inflammation, leprosy-like sarcoidal and palisaded granulomatous inflammation has been documented in literature reports of lues. Herein, we report a 47-year-old man who presented with a 3-month history of a generalized non-pruritic macular and papular rash located on the trunk and extremities. Histopathologically, there was an interstitial arrangement of histiocytes with occasional multinucleated giant cells positioned among collagen bundles without associated necrosis, thereby closely mimicking interstitial granuloma annulare. A clue to the diagnosis was the presence of admixed plasma cells. To the best of our knowledge, this is the first reported case of secondary syphilis showing an interstitial granulomatous pattern mimicking interstitial granuloma annulare.
机译：在未治疗的长期梅毒病变中可观察到肉芽肿组织反应。除了定义不明确的肉芽肿性炎症之外，在烟叶的文献报道中还记录了麻风样结节病和栅栏状肉芽肿性炎症。在此，我们报告了一个47岁的男子，他在躯干和四肢出现了3个月的广泛性非瘙痒性黄斑和丘疹皮疹史。在组织病理学上，组织细胞间质排列，偶尔有多核巨细胞位于胶原束之间，而无相关坏死，从而紧密模仿环形间质肉芽肿。诊断的线索是混合浆细胞的存在。据我们所知，这是首次报告的继发性梅毒病例，表现为模仿环形间质肉芽肿的间质肉芽肿样。

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