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首页> 外文期刊>Journal of drug delivery science and technology >Biophysical techniques for transdermal delivery of iron
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Biophysical techniques for transdermal delivery of iron

机译：铁的透皮递送的生物物理技术

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摘要

Iron deficiency anemia is the one of the major nutritional deficiency disorder. Current conventional treatment options with oral and parenteral iron formulations are associated with limitations and numerous side effects. Transdermal delivery of iron was explored systematically as an alternative treatment option as it is non-invasive and patient compliant. Ferric pyrophosphate was used as the source of iron for transdermal delivery. Biophysical techniques like iontophoresis, electroporation and microporation were explored for the delivery of FPP and in vivo studies were carried out in anemic rat model. Therapeutically required quantities of iron can be delivered using combination of these active techniques.
机译：缺铁性贫血是主要的营养缺乏症之一。当前使用口服和肠胃外铁制剂的常规治疗选择与局限性和许多副作用有关。由于铁的非侵入性和患者顺应性，因此系统地探索了铁的经皮输送作为替代治疗选择。焦磷酸铁用作经皮递送的铁源。探索了诸如离子电渗疗法，电穿孔和微穿孔的生物物理技术来递送FPP，并在贫血大鼠模型中进行了体内研究。可以结合使用这些活性技术来输送治疗所需量的铁。

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