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首页> 外文期刊>Journal of drug assessment >Cost-effectiveness analysis of proton pump inhibitors compared to omeprazole in the healing of reflux oesophagitis
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Cost-effectiveness analysis of proton pump inhibitors compared to omeprazole in the healing of reflux oesophagitis

机译:与奥美拉唑相比质子泵抑制剂治疗反流性食管炎的成本效益分析

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摘要

In 1998, the National Health Service (NHS) in England and Wales spent over £314 million on proton pump inhibitors (PPIs). The National Institute for Clinical Excellence (NICE) guidance on the use of PPIs in dyspepsia advises that the least expensive appropriate PPI be used. Consequently, the objective of this study was to assess the cost-effectiveness of all PPIs for the healing of reflux oesophagitis over 8 weeks from the perspective of the UK's NHS.A decision analysis model was developed using healing rates derived from a systematic review of all PPIs using omeprazole as a common comparator. The economic analysis indicates that esomeprazole is cost-effective compared with all other PPIs currently available for healing reflux oesophagitis.
机译:1998年,英格兰和威尔士国家卫生局(NHS)在质子泵抑制剂(PPI)上花费了超过3.14亿英镑。美国国家临床卓越研究所(NICE)关于在消化不良中使用PPI的指南建议,应使用最便宜的适当PPI。因此,本研究的目的是从英国NHS的角度评估所有PPI在8周内用于治疗反流性食管炎的成本效益。使用奥美拉唑作为常见对照的PPI。经济分析表明,与目前可用于治疗反流性食管炎的所有其他PPI相比,埃索美拉唑具有成本效益。

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