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首页> 外文期刊>Clinical chemistry and laboratory medicine: CCLM >Plasma visfatinicotinamide phosphoribosyltransferase (visfatin/NAMPT) concentration is not related to kidney function in elderly subjects
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Plasma visfatinicotinamide phosphoribosyltransferase (visfatin/NAMPT) concentration is not related to kidney function in elderly subjects

机译:血浆visfatin /烟酰胺磷酸核糖基转移酶(visfatin / NAMPT)的浓度与老年受试者的肾功能无关

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摘要

Background: Studies assessing plasma visfatinicotinamide phosphoribosyltransferase (NAMPT) concentrations in chronic kidney disease with the ELISA method are restricted mainly to subjects with end-stage kidney disease. Therefore, little is known about to what extent glomerular filtration rate (GFR) affects the plasma levels of visfatin/NAMPT. The aim of this study was to assess the relations between circulating visfatin/NAMPT levels and estimated GFR (eGFR), independently of potential con-founders such as inflammation, nutritional status, and insulin resistance in the elderly population.
机译:背景:用ELISA法评估慢性肾脏病中血浆visfatin /烟酰胺磷酸核糖基转移酶(NAMPT)浓度的研究主要限于终末期肾脏病患者。因此,关于肾小球滤过率(GFR)在多大程度上影响visfatin / NAMPT的血浆水平知之甚少。这项研究的目的是评估循环中的visfatin / NAMPT水平与估计的GFR(eGFR)之间的关系,而与潜在的混杂因素(例如老年人中的炎症,营养状况和胰岛素抵抗)无关。

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