Analytical interference by monoclonal immunoglobulins on the direct bilirubin AU Beckman Coulter assay: the benefit of unsuspected diagnosis from spurious results

Garcia-Gonzalez Elena; Gonzalez-Tarancon Ricardo; Aramendia Maite; Rello Luis

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Analytical interference by monoclonal immunoglobulins on the direct bilirubin AU Beckman Coulter assay: the benefit of unsuspected diagnosis from spurious results

机译：单克隆免疫球蛋白对直接胆红素的分析干扰AU Beckman Coulter分析：从假结果中进行意外诊断的益处

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Background: Monoclonal (M) components can interfere with the direct bilirubin (D-Bil) assay on the AU Beckman Coulter instrumentation and produce spurious results, such as D-Bil values greater than total bilirubin (T-Bil) or very lowegative D-Bil values. If properly detected, this interference may uncover undiagnosed patients with monoclonal gammopathy (MG).

机译：背景：单克隆（M）成分会干扰AU Beckman Coulter仪器上的直接胆红素（D-Bil）测定，并产生虚假结果，例如D-Bil值大于总胆红素（T-Bil）或非常低/负D-Bil值。如果正确检测到，这种干扰可能会发现未经诊断的单克隆丙种球蛋白病（MG）。

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《Clinical chemistry and laboratory medicine: CCLM》 |2016年第8期|共7页
作者
Garcia-Gonzalez Elena; Gonzalez-Tarancon Ricardo; Aramendia Maite; Rello Luis;
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正文语种 eng
中图分类诊断学;
关键词
direct bilirubin; interference; monoclonal component; monoclonal gammopathy; paraprotein;

机译：直接胆红素;干扰;单克隆成分;单克隆丙种球蛋白病;副蛋白;

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1. Analytical interference by monoclonal immunoglobulins on the direct bilirubin AU Beckman Coulter assay: the benefit of unsuspected diagnosis from spurious results [J] . Garcia-Gonzalez Elena, Gonzalez-Tarancon Ricardo, Aramendia Maite, Clinical chemistry and laboratory medicine: CCLM . 2016,第8期

机译：单克隆免疫球蛋白对直接胆红素的分析干扰AU Beckman Coulter分析：从假结果中进行意外诊断的益处
2. Analytical evaluation of Diazyme procalcitonin (PCT) latex-enhanced immunoturbidimetric assay on Beckman Coulter AU5800 [J] . Dipalo Mariella, Buonocore Ruggero, Gnocchi Cecilia, Clinical chemistry and laboratory medicine: CCLM . 2015,第4期

机译：在Beckman Coulter AU5800上对重钙降钙素（PCT）乳胶增强免疫比浊法进行分析评估
3. Analytical assessment of the novel homocysteine liquid enzymatic assay on Beckman Coulter AU5800 [J] . Dipalo Mariella, Dipietro Martina, Gnocchi Cecilia, Clinical chemistry and laboratory medicine: CCLM . 2015,第12期

机译：在Beckman Coulter AU5800上进行的新型同型半胱氨酸液体酶测定的分析评估
4. The Roche Elecsys and Siemens-Centaur Thyroglobulin Autoantibody Assays Show Comparable Clinical Performance to the Recently Unavailable Beckman-Coulter Access Thyroglobulin Autoantibody Assay in Identifying Samples with Potentially False-Low Thyroglobulin Measurements Due to Thyroglobulin Autoantibody Interference [O] . Alicia Algeciras-Schimnich, Michael A. Lasho, Karl M. Ness, -1

机译：Roche Elecsys和Siemens-Centaur甲状腺球蛋白自身抗体测定与最近无法获得的Beckman-Coulter甲状腺球蛋白自身抗体测定具有可比的临床性能可鉴定出由于甲状腺球蛋白自身抗体干扰而导致潜在的假低甲状腺球蛋白测定
5. The Roche Elecsys and Siemens-Centaur Thyroglobulin Autoantibody Assays Show Comparable Clinical Performance to the Recently Unavailable Beckman-Coulter Access Thyroglobulin Autoantibody Assay in Identifying Samples with Potentially False-Low Thyroglobulin Measurements Due to Thyroglobulin Autoantibody Interference [O] . Algeciras-Schimnich, Alicia, Lasho, Michael A., Ness, Karl M., 2011

机译：Roche Elecsys和Siemens-Centaur甲状腺球蛋白自身抗体测定与最近无法获得的Beckman-Coulter甲状腺球蛋白自身抗体测定具有可比的临床性能，可鉴定出由于甲状腺球蛋白自身抗体干扰而导致潜在的假低甲状腺球蛋白测定

Analytical interference by monoclonal immunoglobulins on the direct bilirubin AU Beckman Coulter assay: the benefit of unsuspected diagnosis from spurious results

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