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首页> 外文期刊>Journal of applied microbiology >Bacillus subtilis AB1 controls Aeromonas infection in rainbow trout (Oncorhynchus mykiss, Walbaum)
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Bacillus subtilis AB1 controls Aeromonas infection in rainbow trout (Oncorhynchus mykiss, Walbaum)

机译：枯草芽孢杆菌AB1控制虹鳟（Oncorhynchus mykiss，Walbaum）中的气单胞菌感染

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Aim: To develop a probiotic with effectiveness against Aeromonas sp., which was pathogenic to rainbow trout. Methods and Results: When Bacillus subtilis AB1, which was obtained from fish intestine, was administered for 14 days to rainbow trout in feed at a concentration of 10(7) cells per gram either as viable, formalized or sonicated cells or as cell-free supernatant, the fish survived challenge with the pathogen. AB1 stimulated immune parameters, specifically stimulating respiratory burst, serum and gut lysozyme, peroxidase, phagocytic killing, total and alpha 1-antiprotease and lymphocyte populations. Conclusions: Bacillus subtilis AB1 was effective as a probiotic at controlling infections by a fish-pathogenic Aeromonas sp. in rainbow trout. Significance and Impact of the Study: Disease control in fish is possible by means of the oral application of live and inactivated cells and their subcellular components with the mode of action reflecting stimulation of the innate immune response.
机译：目的：开发一种对彩虹鳟鱼致病的益生菌，对付气单胞菌。方法和结果：当从鱼肠中获得的枯草芽孢杆菌AB1施用给饲料中的虹鳟鱼14天时，其浓度为每克10（7）个活细胞，形式化细胞或超声细胞或无细胞上清液中，鱼在病原体攻击下存活下来。 AB1刺激了免疫参数，特别是刺激了呼吸爆发，血清和肠道溶菌酶，过氧化物酶，吞噬细胞杀伤力，总α1-抗蛋白酶和淋巴细胞群。结论：枯草芽孢杆菌AB1作为益生菌可有效控制鱼类致病性气单胞菌感染。在虹鳟鱼。该研究的意义和影响：可以通过口服应用活细胞和灭活细胞及其亚细胞成分，并以反映先天免疫反应刺激的作用方式，对鱼类进行疾病控制。

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