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首页> 外文期刊>Journal of dentistry >An in vitro model for the study of chemical exchange between glass ionomer restorations and partially demineralized dentin using a minimally invasive restorative technique
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An in vitro model for the study of chemical exchange between glass ionomer restorations and partially demineralized dentin using a minimally invasive restorative technique

机译：使用微创修复技术研究玻璃离聚物修复体和部分脱矿质牙本质之间化学交换的体外模型

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Objectives: This study was designed to validate an in vitro model of the Atraumatic Restorative Technique (ART). This model allowed in depth analyses of the migration of apatite forming Sr and F, from a glass-ionomer, Fuji IXGP (GC Corporation, Tokyo, Japan), into partly demineralized dentine. The second objective was to study the effects of the levels of mineral loss on such ionic exchange. Methods: Artificial lesions were created in thirty third molars, which were divided into three groups based on time of exposure to the demineralizing solution (7, 14 and 21 days). These were restored with Fuji IXGP and left for 21 days. The method of analysis was electron probe microanalysis (EPMA) with wavelength dispersive spectrometry (WDS). This combination can yield both qualitative identification of elements as well as quantitative compositional information, with a minimum detection limit of 0.01%. Results: The results indicated that there was no significant difference in the levels of Ca and P from the control and test sides for all three groups of demineralized dentine. The differences in the depth of penetration and the amount of Sr and F between control and test were significant. Conclusions: The validity of the in vitro model was confirmed. There was migration of both strontium and fluorine to the artificially demineralized dentine in a pattern consistent with remineralization and similar to what was observed in a previous in vivo study.
机译：目的：本研究旨在验证无创伤修复技术（ART）的体外模型。该模型允许深入分析形成磷灰石的Sr和F从玻璃离聚物Fuji IXGP（GC Corporation，日本东京）到部分脱矿质牙本质的迁移。第二个目的是研究矿物质损失水平对这种离子交换的影响。方法：在第三十三颗磨牙中产生人造病变，根据暴露在脱盐溶液中的时间（7天，14天和21天）将其分为三组。这些已用Fuji IXGP修复，并保留了21天。分析方法是电子探针微分析（EPMA）和波长色散光谱（WDS）。这种结合可以产生元素的定性鉴定和定量组成信息，最低检出限为0.01％。结果：结果表明，所有三组脱钙牙本质的对照组和测试组的钙和磷水平均无显着差异。对照和试验之间的渗透深度以及Sr和F的含量差异显着。结论：证实了体外模型的有效性。锶和氟都以与再矿化相一致的方式迁移到了人工脱矿的牙质中，与先前的体内研究中观察到的情况相似。

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