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首页> 外文期刊>Journal of dentistry >Preventive effects of dentifrice containing 5000ppm fluoride against dental erosion in situ.
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Preventive effects of dentifrice containing 5000ppm fluoride against dental erosion in situ.

机译：含5000ppm氟化物的洁牙剂对牙齿侵蚀的预防作用。

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OBJECTIVE: To evaluate the effectiveness of a dentifrice with 5000ppm fluoride in preventing dental erosion by orange juice in situ in comparison to a control dentifrice with 1450ppm fluoride. METHODS: This was a double-blind and randomized clinical study with a cross-over design. Sixteen subjects wore an intra-oral appliance containing two enamel disks with an exposed surface of approximately 2mmx5mm. Enamel disks in the study group were treated with a dentifrice with 5000ppm fluoride and in the control group with 1450ppm fluoride. The subjects rinsed with slurries of study dentifrices for one minute before immersing the enamel disks in 250ml orange Juice four times in an 8-h period daily. The treatment procedure was repeated for three 5-day phases for each dentifrice. Enamel erosion was measured after each 5-day treatment phase using a focus-variation 3D scanning microscopy. Medians and inter-quartile ranges (IQR) of mean erosion depth were compared between the groups. RESULTS: The mean erosion depths of enamel varied greatly amongst the subjects. Enamel treated with 5000ppm fluoride had less erosion (median 5.7mum, IQR 4.5mum) as compared to the control (median 12.6mum, IQR 12.3mum) after 15 days of fluoride treatment and erosive challenge cycles (p<0.05). CONCLUSIONS: Enamel treated with 5000ppm fluoride had significantly improved resistance to erosion by orange juice. Periodic application of 5000ppm fluoride may be beneficial in individuals at risk of acidic erosion associated with soft drink consumptions.
机译：目的：评估含5000ppm氟化物的洁牙剂与含1450ppm氟化物的对照洁牙剂相比，预防橙汁原位牙齿侵蚀的有效性。方法：这是一项具有交叉设计的双盲和随机临床研究。 16名受试者佩戴了一个口腔内矫治器，其中包含两个搪瓷盘，其暴露表面约为2mmx5mm。研究组的牙釉质盘用含5000ppm氟化物的洁牙剂治疗，而对照组则用1450ppm的氟化物治疗。受试者用研究洁牙剂的浆液冲洗1分钟，然后每天8小时将釉质盘浸入250毫升橙汁中四次。对于每个洁齿剂，重复治疗过程三个5天的阶段。在每个5天的治疗阶段后，使用焦点变化3D扫描显微镜对牙釉质侵蚀进行测量。比较了两组之间平均侵蚀深度的中位数和四分位间距（IQR）。结果：受试者的牙釉质平均侵蚀深度差异很大。经过15天的氟化物处理和侵蚀性腐蚀循环后，与对照组（中位数12.6mum，IQR 12.3mum）相比，用5000ppm氟化物处理的牙釉质的侵蚀较少（中位数5.7mum，IQR 4.5mum）（p <0.05）。结论：用5000ppm氟化物处理的搪瓷具有显着提高的抗橙汁侵蚀能力。定期使用5000ppm的氟化物可能对那些与软饮料消费有关的酸蚀风险的人有益。

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