Five regulatory genes detected by matching signatures of eQTL and GWAS in psoriasis

Yin Xianyong; Cheng Hui; Lin Yan; Fan Xing; Cui Yong; Zhou Fusheng; Shen Changbing; Zuo Xianbo; Zheng Xiaodong; Zhang Weijia; Yang Sen; Zhang Xuejun

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Five regulatory genes detected by matching signatures of eQTL and GWAS in psoriasis

机译：通过匹配eQTL和GWAS在牛皮癣中的特征检测到五个调节基因

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Background: Psoriasis is a common immune-mediated inflammatory skin disease with strong genetic dispositions. Although more than 40 susceptibility loci have been revealed mostly through psoriasis genome wide association studies, genetic variants with small effect remain to be identified.

机译：背景：牛皮癣是一种常见的免疫介导的炎症性皮肤病，具有很强的遗传特性。尽管已经通过牛皮癣全基因组关联研究揭示了40多个易感基因座，但仍需鉴定效果不大的遗传变异。

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《Journal of dermatological science》 |2014年第2期|共4页
作者
Yin Xianyong; Cheng Hui; Lin Yan; Fan Xing; Cui Yong; Zhou Fusheng; Shen Changbing; Zuo Xianbo; Zheng Xiaodong; Zhang Weijia; Yang Sen; Zhang Xuejun;
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正文语种 eng
中图分类皮肤病学与性病学;
关键词
Psoriasis; Genome wide association; Susceptibility gene;

机译：牛皮癣;全基因组关联;易感基因;

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专利

1. Five regulatory genes detected by matching signatures of eQTL and GWAS in psoriasis [J] . Yin Xianyong, Cheng Hui, Lin Yan, Journal of dermatological science . 2014,第2期

机译：通过匹配eQTL和GWAS在牛皮癣中的特征检测到五个调节基因
2. Colocalization of GWAS and eQTL Signals Detects Target Genes [J] . Hormozdiari Farhad, van de Bunt Martijn, Segre Ayellet V., The American Journal of Human Genetics . 2016,第6期

机译：GWAS和eQTL信号的共定位可检测靶基因
3. Sherlock: Detecting gene-disease associations by matching patterns of expression QTL and GWAS [J] . HeX., FullerC.K., SongY., The American Journal of Human Genetics . 2013,第5期

机译：Sherlock：通过匹配表达模式QTL和GWAS检测基因-疾病关联
4. eQTL epistasis: Detecting complex interaction effects between multiple loci from eQTL data [C] . Kang M., Li S., Liu C., IEEE International Conference on Bioinformatics and Biomedicine . 2013

机译：eQTL上位性：根据eQTL数据检测多个基因座之间的复杂相互作用
5. Spatial scales of mixing and natal source contributions of salmon populations in the coastal ocean detected by otolith and genetic signatures of origin. [D] . Barnett-Johnson, Rachel. 2007

机译：通过耳石和起源的遗传特征检测到沿海海洋鲑鱼种群的混合尺度和成年来源贡献。
6. Colocalization of GWAS and eQTL Signals Detects Target Genes [O] . Farhad Hormozdiari, Martijn van de Bunt, Ayellet V. Segrè, 2016

机译：GWAS和eQTL信号的共定位可检测靶基因
7. Colocalization of GWAS and eQTL signals detects target genes [O] . Hormozdiari, F, van de Bunt, M, Segrè, AV, 2016

机译：GWAS和eQTL信号的共定位可检测靶基因
8. Use of eQTL Analysis for the Discovery of Target Genes Identified by GWAS [R] . Thibodeau, S 2014

机译：使用eQTL分析发现GWas识别的目标基因

Five regulatory genes detected by matching signatures of eQTL and GWAS in psoriasis

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