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首页> 外文期刊>Journal of dentistry >Effect of fluoride sustained slow-releasing device on fluoride, phosphate and calcium levels in plaque biofilms over time measured using ion chromatography
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Effect of fluoride sustained slow-releasing device on fluoride, phosphate and calcium levels in plaque biofilms over time measured using ion chromatography

机译:离子色谱法测定氟持续缓释装置对斑块生物膜中氟,磷酸盐和钙水平的影响

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Objectives: To determine whether there are any differences in fluoride (F), calcium (Ca) or phosphate (PO 4) concentrations in natural plaque biofilms between the upper right and left quadrants using a fluoride sustained slow-releasing device (FSSRD) placed in the upper right quadrant after 7 and 21 days. To report and validate a new methodology in measuring very low concentrations of F in dental plaque and saliva using ion chromatography. Methods: Twenty-one participants were divided into two groups with 11 participants in group one and 10 in group two. Each participant had a FSSRD attached to the upper right second permanent molar and two plaque generating devices (PGDs) attached to the upper right and left first permanent molars. The PGDs were recovered after 7 days in group one and 21 days in group two. Results: At both 7 and 21 days (right, left), F (1.081 ± 1.517 ppm, 0.736 ± 0.840 ppm) and (0.459 ± 0.888 ppm, 0.203 ± 0.139 ppm), PO 4 (1053 ± 533 ppm, 654 ± 246 ppm) and (865 ± 1099 ppm, 474 ± 304 ppm) and Ca (136 ± 132 ppm, 74 ± 36 ppm) and (130 ± 109 ppm, 77 ± 24 ppm), were higher in the quadrant containing the FSSRD but not significantly so (p 0.05). Fluoride and PO 4 fell in both quadrants between 7 and 21 days, though not significantly. Conclusions: Intriguingly while not statistically significant, 21 day plaque contained less fluoride than those investigated after 7 days. While the data was not statistically significant, it seems possible that F, Ca and PO 4 accumulated around the device to a limited extent but were washed away fairly quickly and distributed around the oral cavity. Clinical importance: The FSSRD was found to reduce dmfs/DMFS by 76% and raise salivary F levels by ~10 folds. This device is very helpful in reducing dental decay where compliance is impaired such as in patients with special needs. This study further investigates the anti-cariogenic effect of this device.
机译:目的:使用放置在体内的氟化物缓缓释放装置(FSSRD),确定右上象限和左上象限之间天然噬菌斑生物膜中氟化物(F),钙(Ca)或磷酸盐(PO 4)的浓度是否存在差异。 7天和21天后,右上象限。报告并验证使用离子色谱法测量牙菌斑和唾液中极低浓度F的新方法。方法:将21名参与者分为两组,第一组11名参与者,第二组10名参与者。每个参与者的FSSRD都附着在右上第二恒磨牙上,两个菌斑生成装置(PGD)附着在右上和左上第一恒磨牙上。第一组7天和第二组21天后,PGD恢复。结果:在第7天和第21天(左右),F(1.081±1.517 ppm,0.736±0.840 ppm)和(0.459±0.888 ppm,0.203±0.139 ppm),PO 4(1053±533 ppm,654±246) ppm)和(865±1099 ppm,474±304 ppm)和Ca(136±132 ppm,74±36 ppm)和(130±109 ppm,77±24 ppm)在含有FSSRD的象限中较高,但没有显着如此(p> 0.05)。氟化物和PO 4在7至21天的两个象限中均下降,尽管不明显。结论:有趣的是,尽管没有统计学意义,但21天的斑块中的氟化物含量比7天后的氟化物少。尽管数据在统计上并不显着,但F,Ca和PO 4可能会在设备周围有限程度地积累,但很快被冲走并分布在口腔周围。临床重要性:发现FSSRD可使dmfs / DMFS降低76%,唾液F水平提高约10倍。该设备对于减少顺应性受损(例如有特殊需求的患者)的蛀牙非常有帮助。这项研究进一步研究了该装置的抗龋齿作用。

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