A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice

Nesterovitch Andrew B.; Arbieva Zarema; Toth Daniel M.; Tharp Michael D.; Glant Tibor T.

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A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice

机译：差异基因表达研究：Ptpn6（SHP-1）功能不足会在小鼠中导致嗜中性皮肤病样疾病（NDLD）

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Background: Irradiated syngeneic wild-type mice developed the same neutrophilic dermatosis-like disease (NDLD) after adoptive transfer of bone marrow cells from Ptpn6(meb2/meb2) mutant mice.

机译：背景：辐照的同基因野生型小鼠从Ptpn6（meb2 / meb2）突变小鼠过继转移骨髓细胞后，发展出相同的嗜中性皮肤病样疾病（NDLD）。

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来源
《Journal of dermatological science》 |2016年第1期|共9页
作者
Nesterovitch Andrew B.; Arbieva Zarema; Toth Daniel M.; Tharp Michael D.; Glant Tibor T.;
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正文语种 eng
中图分类皮肤病学与性病学;
关键词
Autoinflammatory; Motheaten; Neutrophilic dermatoses; Pyoderma gangrenosum; Gene expression microarray; SHP-1;

机译：自发炎症;Moateaten;中性皮肤病;坏疽性脓皮病;基因表达芯片;SHP-1;

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1. A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice [J] . Nesterovitch Andrew B., Arbieva Zarema, Toth Daniel M., Journal of dermatological science . 2016,第1期

机译：差异基因表达研究：Ptpn6（SHP-1）功能不足会在小鼠中导致嗜中性皮肤病样疾病（NDLD）
2. Spontaneous Insertion of a B2 Element in the Ptpn6 Gene Drives a Systemic Autoinflammatory Disease in Mice Resembling Neutrophilic Dermatosis in Humans [J] . Andrew B. Nesterovitch, Sandor Szanto, Andrea Gonda, The American journal of pathology. . 2011,第4期

机译：在Ptpn6基因中自发插入B2元素会在类似于中性粒细胞性皮肤病的小鼠中引发全身性自身炎症性疾病
3. SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activation [J] . Ren-In You, Ching-Liang Chu 细胞与分子免疫学：英文版 . 2017,第011期
4. Differential expression of genes encoding CD30L and P-selectin in cattle with Johne's disease: Progress toward a diagnostic gene expression signature [C] . Skovgaard K, Pudrith CB, Grell SN, International Colloquium on Paratuberculosis . 2007

机译：牛与Johne疾病中CD30L和P-Selectin的基因的差异表达：诊断基因表达签名的进展
5. Evaluating Differential Gene Expression Using RNA-Sequencing: A Case Study in Diet-Induced Mouse Model Associated With Non-Alcoholic Fatty Liver Disease (NAFLD) and CXCL12-vs-TGFβ Induced Fibroblast to Myofibroblast Phenoconversion [D] . Samadder, Arpa 2019

机译：使用RNA测序评估差异基因表达：饮食诱导的小鼠模型与非酒精脂肪肝疾病（NAFLD）和CXCL12-VS-TGFβ诱导成纤维细胞与肌纤维细胞异胆脱色的案例研究
6. SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activation [O] . Ren-In You, Ching-Liang Chu 2017

机译：SHP-1（PTPN6）阻止炎症：通过阻止Syk激酶激活来限制IL-1α介导的嗜中性皮肤病
7. 498 Gene expression signature in the bone marrow and skin of Ptpn6-insufficient mice with neutrophilic dermatosis-like disease (NDLD) [O] . A. Nesterovitch, Z. Arbieva, D. Toth, 2016

机译：498基因表达患者在骨髓和皮肤皮肤的皮肤上，与嗜中性皮肤病样疾病（NDLD）

A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice

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