首页> 外文期刊>Journal of dermatological science >Plasma platelet activation markers in patients with atopic dermatitis and concomitant allergic diseases.
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Plasma platelet activation markers in patients with atopic dermatitis and concomitant allergic diseases.

机译:特应性皮炎和伴发性过敏性疾病患者的血浆血小板活化标志物。

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摘要

Apart from a well-established role of platelets in haemostasis, their activation may contribute to the development of chronic allergic inflammation [1]. Platelets release a number of potent mediators of vasodilatation and increased vascular permeability [2], and chemoattractants promoting migration of leukocytes to the site of allergic inflammation [3]. Atopic dermatitis (AD) is a chronic skin disorder of the complex pathogenesis involving immediate hypersensitivity and cellular responses, characterized by skin inflammation and itching [4].
机译:除了血小板在止血中已确立的作用外,它们的活化还可能导致慢性变态反应性炎症的发展[1]。血小板释放出许多有效的血管舒张介质,增加血管通透性[2],而趋化剂促进白细胞向过敏性炎症部位迁移[3]。特应性皮炎(AD)是一种复杂的发病机制的慢性皮肤病,涉及立即的超敏反应和细胞反应,特征是皮肤发炎和瘙痒[4]。

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