Association between T-lymphocyte regulatory gene CTLA4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1*08 in Japanese patients with psoriasis vulgaris.

Muto M; Deguchi H; Tanaka A; Inoue T; Ichimiya M

首页> 外文期刊>Journal of dermatological science >Association between T-lymphocyte regulatory gene CTLA4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1*08 in Japanese patients with psoriasis vulgaris.

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Association between T-lymphocyte regulatory gene CTLA4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1*08 in Japanese patients with psoriasis vulgaris.

机译：日本寻常型银屑病患者中外显子1 49位T淋巴细胞调节基因CTLA4单核苷酸多态性与HLA-DRB1 * 08之间的关联。

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Psoriasis vulgaris (PV) is a multifactorial skin disease involving T lymphocyte-mediated inflammation. The major genetic determinant of psoriasis is PSORS1, which accounts for more than 30% of the heritability of PV. A recent genome-wide association study revealed that the human leukocyte antigen (HLA) complex, particularly HLA-Cw*0602, is the most plausible candidate gene among various ethnicities [1].

机译：寻常型牛皮癣（PV）是涉及T淋巴细胞介导的炎症的多因素皮肤病。牛皮癣的主要遗传决定因素是PSORS1，其占PV遗传力的30％以上。最近的全基因组关联研究显示，人类白细胞抗原（HLA）复合体，尤其是HLA-Cw * 0602，是各个种族中最合理的候选基因[1]。

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《Journal of dermatological science》 |2011年第1期|共2页
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Muto M; Deguchi H; Tanaka A; Inoue T; Ichimiya M;
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正文语种 eng
中图分类皮肤病学与性病学;
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1. Association between T-lymphocyte regulatory gene CTLA4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1*08 in Japanese patients with psoriasis vulgaris. [J] . Muto M, Deguchi H, Tanaka A, Journal of dermatological science . 2011,第1期

机译：日本寻常型银屑病患者中外显子1 49位T淋巴细胞调节基因CTLA4单核苷酸多态性与HLA-DRB1 * 08之间的关联。
2. Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28. [J] . Itoda Masaya, Saito Yoshiro, Soyama Akiko, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2002,第4期

机译：在源自日本人的72种成熟细胞系中发现的ABCC2（cMOAT / MRP2）基因多态性：5'非翻译区的单核苷酸多态性与外显子28之间的关联。
3. Cytotoxic T-lymphocyte antigen 4 (CTLA4) +49AG and CT60 gene polymorphisms in Alopecia Areata: A case-control association study in the Italian population [J] . MegiorniF., MoraB., MaxiaC., Archives of dermatological research. . 2013,第7期

机译：脱发的细胞毒性T淋巴细胞抗原4（CTLA4）+ 49AG和CT60基因多态性：意大利人群的病例对照研究
4. ASSOCIATION OF THE EXON 9 SINGLE-NUCLEOTIDE POLYMORPHISM OF CAPfli WITH BEEF TENDERNESS [C] . A. Esmailizadeh Koshkoih, C.D.K. Bottema, Z.A. Kruk, Conference of the Association of the Advancement of Animal Breeding and Genetics . 2005

机译：外显子9单核苷酸多态性的Capfli与牛肉压痛
5. Effects of Single Nucleotide Polymorphisms (SNPs) on RNASEL-Mediated Induction of Apoptotic Genes and Their Association with Sporadic Prostate Cancer Risk. [D] . Johnson, Jabril Rahim. 2016

机译：单核苷酸多态性（SNPs）对RNASEL介导的凋亡基因诱导及其与散发性前列腺癌风险的关系的影响。
6. No association of the cytotoxic T-lymphocyte associated gene CTLA4 +49A/G polymorphisms with Crohn’s disease and ulcerative colitis in Hungarian population samples [O] . Lili Magyari, Bernadett Faragó, Judit Bene, 2007

机译：匈牙利人群样本中细胞毒性T淋巴细胞相关基因CTLA4 + 49A / G多态性与克罗恩病和溃疡性结肠炎无关联
7. No association of the cytotoxic T-lymphocyte associated gene CTLA4 +49A/G polymorphisms with Crohn’s disease and ulcerative colitis in Hungarian population samples [O] . Magyari Lili, Faragó Bernadett, Bene Judit, 2007

机译：匈牙利人群样本中细胞毒性T淋巴细胞相关基因CTLA4 + 49A / G多态性与克罗恩病和溃疡性结肠炎无关联

Association between T-lymphocyte regulatory gene CTLA4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1*08 in Japanese patients with psoriasis vulgaris.

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