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首页> 外文期刊>Journal of dermatological science >Integral hair lipid in human hair follicle.
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Integral hair lipid in human hair follicle.

机译：人毛囊中的整体毛脂。

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摘要

Integral hair lipid (IHL) is bound to the keratinized cell surface to make an environmentally resistant lipid envelope. It is mainly positioned on the hair cuticle and inner root sheath. IHL in the hair follicle may regard as hair barrier to be similar to the epidermal lipid layer functioning as skin barrier. Major constituents of IHL are fatty acid, phytosphingosine, ceramide in decreasing order. Minor constituents of IHL are cholesterol, cholesterol sulfate and cholesterol oleate. Cuticle or cortical cell surface in hair are abundant in fatty acids unlike the keratinized area of epidermis or sebaceous gland, and about 30-40% of such fatty acids are composed of 18-methyl-eicosanoic acid which is known to be bound to proteins by ester or thioester bond. Various factors including moisture, solvent, oxidative damage during bleaching or permanent waving affect IHL. Photochemical changes also can occur in IHL as well as in hair protein and hair pigment. Lipid metabolism is thought to play an essential role in lipid envelope of hair, but also involvement in hair development and function.
机译：整体毛发脂质（IHL）与角化细胞表面结合，形成对环境无害的脂质包膜。它主要位于毛鳞片和内根鞘上。毛囊中的IHL可以看作是头发屏障，类似于起皮肤屏障作用的表皮脂质层。人道法的主要成分是脂肪酸，植物鞘氨醇，神经酰胺，降序排列。 IHL的次要成分是胆固醇，胆固醇硫酸盐和胆固醇油酸酯。与表皮或皮脂腺的角质化区域不同，头发中的表皮或皮层细胞表面富含脂肪酸，此类脂肪酸中约30-40％由18-甲基-二十二酸组成，已知该酸通过蛋白质与蛋白质结合酯或硫酯键。 IHL受各种因素影响，包括水分，溶剂，漂白过程中的氧化损伤或永久起伏。光化学变化也可能发生在人道法以及头发蛋白和染发剂中。脂质代谢被认为在头发的脂质包膜中起重要作用，但也参与头发的发育和功能。

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