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Regulatory T cells in cutaneous immune responses.

机译:皮肤免疫反应中的调节性T细胞。

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摘要

Regulatory T cells (Treg) are a subset of T cells with strong immunosuppressive activity. In the skin, it has recently been revealed that Treg play important roles not only in the maintenance of skin homeostasis but also in the regulation of the immune responses, such as contact hypersensitivity and atopic dermatitis. Furthermore, the skin plays important roles in the induction of Treg in the periphery. In this review, we will provide an overview of the mechanism of Treg-mediated immunosuppression and discuss the role of Treg in the skin.
机译:调节性T细胞(Treg)是具有强大免疫抑制活性的T细胞的子集。在皮肤中,最近发现,Treg不仅在维持皮肤稳态中起着重要作用,而且在免疫反应的调节中也起着重要作用,例如接触性超敏反应和特应性皮炎。此外,皮肤在外周Treg的诱导中起重要作用。在这篇综述中,我们将概述Treg介导的免疫抑制机制,并讨论Treg在皮肤中的作用。

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