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Biological contribution of UVA wavelengths in non extreme daily UV exposure

机译:UVA波长在非极端日照中的生物贡献

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摘要

Chronic sun exposure leads to long term clinical skin alterations such as photoaging and photocarcinogenesis, involving both ultraviolet B (UVB) (280-320 nm) and UVA (320-400 nm) wavelengths. To study the impact of solar UV exposure occurring in most outdoor activities, a non-zenithal UV spectrum has been defined as standard ultraviolet daylight spectrum with a UVA to UVB irradiance ratio of around 27, corresponding to 96.5% UVA and 3.5% UVB. This non zenithal exposure can be reproduced in laboratory experimentations using a daily UV radiation (DUVR) spectrum [1], including a high and constant proportion of UVA wavelengths. Clinical and biophysical alterations as well as dermal and epidermal changes have been reported in human following exposure to repeated sub-erythemal doses of DUVR [2].
机译:长期暴露于阳光下会导致长期的临床皮肤改变,例如光老化和光致癌作用,涉及紫外线B(UVB)(280-320 nm)和UVA(320-400 nm)波长。为了研究在大多数户外活动中发生的太阳紫外线暴露的影响,非天顶紫外线光谱已被定义为标准紫外线日光光谱,其UVA与UVB的辐照比约为27,分别相当于96.5%的UVA和3.5%的UVB。这种非天顶曝光可以在实验室实验中使用每日UV辐射(DUVR)光谱[1]复制,其中包括高比例的恒定UVA波长。反复重复亚红剂量的DUVR暴露于人后,临床和生物物理改变以及皮肤和表皮改变已有报道[2]。

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