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首页> 外文期刊>Journal of cosmetic dermatology >Formulations of hydrogels and lipogels with vitamin E
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Formulations of hydrogels and lipogels with vitamin E

机译：含维生素E的水凝胶和脂凝胶制剂

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Vitamin E, a topically administered antioxidant, reduces erythema, photoaging, photo-carcinogenesis, edema, and skin hypersensitivity associated with exposure to ultraviolet B (UVB) radiation. Virgin olive oil, which also has antioxidant properties, reduces the number of, and delays the onset of skin cancer induced by UVB radiation when used after sunbathing. Topical use after sunbathing of formulations that contain virgin olive oil and vitamin E may therefore reduce the number and delay the onset of UVB-related skin cancer in humans. We designed formulations of gels with olive oil (lipogels) and hydrogels containing 2% tocopherol. The formulations were optimized on the basis of rheological, organoleptic, biopharmaceutical, and cosmetic criteria. Different formulae for hydrogels with vitamin E were ideal for application after exposure to solar radiation because of their good organoleptic properties. Vitamin E lipogels are of potential use in cosmetics such as locally acting anti-aging treatments because of the antioxidant effects of vitamin E.
机译：维生素E是一种局部施用的抗氧化剂，可减少红斑，光老化，光致癌作用，水肿和与紫外线B（UVB）辐射有关的皮肤超敏反应。初榨橄榄油在日光浴后使用时，还具有抗氧化性能，可减少UVB辐射引起的皮肤癌数量并延迟其发作。因此，在日光浴后局部使用含初榨橄榄油和维生素E的制剂，可以减少人体内与UVB相关的皮肤癌的数量并延缓其发作。我们设计了含有橄榄油（脂凝胶）和含有2％生育酚的水凝胶的凝胶配方。根据流变学，感官，生物制药和化妆品标准优化配方。含有维生素E的水凝胶的不同配方，由于其良好的感官特性，非常适合在暴露于太阳辐射后使用。由于维生素E的抗氧化作用，维生素E脂凝胶可潜在地用于化妆品中，例如局部抗衰老治疗。

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