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首页> 外文期刊>Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology >Continuous insulin infusion is associated with a reduced post-surgical length of stay, but not with the complication rate, in patients with diabetes mellitus undergoing coronary artery bypass graft
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Continuous insulin infusion is associated with a reduced post-surgical length of stay, but not with the complication rate, in patients with diabetes mellitus undergoing coronary artery bypass graft

机译：在接受冠状动脉搭桥术的糖尿病患者中，连续输注胰岛素与减少术后住院时间有关，但与并发症发生率无关

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Objective: To establish if glucose management with continuous intravenous insulin infusion (CII) in the early post-operative period after coronary artery bypass graft (CABG) surgery is associated with complication rate and length of hospital stay (LOS) in patients with diabetes mellitus (DM). Research design and methods: We reviewed the records of 587 patients with DM who underwent CABG from January 1999 until January 2008; 316 patients were placed on CII, while 271 patients were treated with subcutaneous insulin. We examined patient age, glycated hemoglobin (HgbA1c), 24- and 72-h post-operative average capillary blood glucose (CBG), length of stay (LOS), and the rate of complications. Results: There was no difference in HgbA1c between the groups. Mean CBG values at both 24 h and 72 h remained the same in the CII group (167 mg/dl), while in the non-CII group they were 194 mg/dl and 189 mg/dl, respectively (p<0.001 between the groups). Post-surgical median LOS was 6 days in the CII group and 6.5 days in the non-CII group (p=0.003). Complications occurred at similar rate (in 10% and 11% of patients) in the two groups. Conclusions: CII is associated with a reduced post-surgical LOS in patients with DM who undergo CABG.
机译：目的：建立糖尿病患者冠状动脉搭桥术（CABG）术后术后早期连续静脉输注胰岛素（CII）的血糖管理与并发症发生率和住院时间（LOS）是否相关（ DM）。研究设计和方法：我们回顾了1999年1月至2008年1月间587例行CABG的DM患者的记录。 316名患者接受了CII治疗，而271名患者接受了皮下胰岛素治疗。我们检查了患者的年龄，糖化血红蛋白（HgbA1c），术后24和72小时的平均毛细血管血糖（CBG），住院时间（LOS）以及并发症的发生率。结果：HgbA1c在两组之间没有差异。 CII组在24 h和72 h的平均CBG值均保持不变（167 mg / dl），而在非CII组，它们的平均CBG值分别为194 mg / dl和189 mg / dl（p <0.001组）。 CII组的术后中位LOS为6天，非CII组为6.5天（p = 0.003）。两组的并发症发生率相似（分别在10％和11％的患者中）。结论：CII与接受CABG的DM患者的术后LOS降低有关。

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