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首页> 外文期刊>Journal of endotoxin research >A descriptive study of the variation in baseline levels of antiendotoxin core antibodies between US and UK populations.
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A descriptive study of the variation in baseline levels of antiendotoxin core antibodies between US and UK populations.

机译：对美国和英国人群之间抗内毒素核心抗体基线水平变化的描述性研究。

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摘要

Low levels of naturally occurring antibodies to the core section of endotoxin (EndoCAb) have been shown to be predictors of poor outcome following major surgery. We performed a retrospective study comparing pre-operative levels in US surgical patients, UK surgical patients and healthy volunteers. Both IgM and IgG EndoCAb levels were higher in the US surgical patients when compared with the other groups (approximately twice as high in the case of IgG EndoCAb). This may reflect genetic or environmental variability between the patient groups, differences in the disease processes, the disparity in the delivery of health care between the two countries or degradation of the samples in transfer.
机译：内毒素核心部分（EndoCAb）天然产生的抗体水平低，已被证明是大手术后预后不良的预兆。我们进行了一项回顾性研究，比较了美国手术患者，英国手术患者和健康志愿者的术前水平。与其他组相比，美国外科手术患者的IgM和IgG EndoCAb含量均较高（在IgG EndoCAb情况下约为两倍）。这可能反映出患者群体之间的遗传或环境差异，疾病过程的差异，两国之间医疗服务的差异或转移样本的降解。

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