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首页> 外文期刊>Journal of experimental & clinical cancer research : >Focus on the histologic diversity in primary and lymph node lesions and the outcome of gastric cancer.
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Focus on the histologic diversity in primary and lymph node lesions and the outcome of gastric cancer.

机译：关注原发和淋巴结病变的组织学多样性以及胃癌的结局。

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摘要

According to the Japanese Classification of Gastric Carcinoma, one predominant type should be selected to represent the histology of the carcinoma. The authors investigated the relationship among the histologic variables of primary lesions, metastatic lesions and the outcome of patients. A total of 155 patients with node-positive gastric carcinoma were examined. According to the histologic diversity, histologic grades were assigned from 1 to 4 regardless of the predominant histologic type. A larger number of histologic types composing not the primary lesions, but metastatic lymph nodes, were associated with an increasing frequency of advanced stage tumors. On the prognosis by number of histologic types composing the primary tumor and the metastatic lymph nodes, there were significant differences except between the histologic type-2 and histologic type-3 groups in the only metastatic lymph nodes. In conclusion, patients with a greater number of histologic types composing lymph node metastases had poorerprognosis than with a small number of histologic types. Histologic diversity within metastatic lymph node was thought to be important for determining the prognosis of patients with gastric cancer.
机译：根据日本胃癌分类，应选择一种主要类型来代表癌的组织学。作者研究了原发性病变，转移性病变的组织学变量与患者预后之间的关系。共检查155例淋巴结阳性胃癌患者。根据组织学多样性，无论主要的组织学类型如何，组织学等级从1到4分配。并非主要病变而是转移性淋巴结组成的大量组织学类型与晚期肿瘤的发生频率增加相关。就组成原发性肿瘤和转移性淋巴结的组织学类型的预后而言，除了仅有转移性淋巴结的组织学2型和组织学3型组之间存在显着差异。总之，与少量组织学类型相比，具有更多组织学类型构成淋巴结转移的患者预后较差。人们认为转移性淋巴结内的组织学多样性对于确定胃癌患者的预后至关重要。

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