ABC synthesis and antitumor activity of a series of Annonaceous acetogenin analogs with a threo, trans, threo, trans, threo-bis-tetrahydrofuran core unit.

Marshall JA; Sabatini JJ; Valeriote F

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ABC synthesis and antitumor activity of a series of Annonaceous acetogenin analogs with a threo, trans, threo, trans, threo-bis-tetrahydrofuran core unit.

机译：一系列具有苏式，反式，苏式，反式，苏式-双-四氢呋喃核心单元的Annnonaceous acetogenin类似物的ABC合成和抗肿瘤活性。

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摘要

Side-chain analogs of Annonaceous acetogenins with a threo, trans, threo, trans, threo-bis-tetrahydrofuran core unit have been prepared and tested for cytotoxicity against HCT-116 human colon cancer cells.

机译：已经制备了具有苏式，反式，苏式，反式，苏式-双-四氢呋喃核心单元的番荔枝产乙酸甘油酯的侧链类似物，并测试了其对HCT-116人结肠癌细胞的细胞毒性。

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《Bioorganic and Medicinal Chemistry Letters》 |2007年第9期|共4页
作者
Marshall JA; Sabatini JJ; Valeriote F;
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正文语种 eng
中图分类药学;生物化学;
关键词
analogs; tetrahydrofuran; alcoholic beverage control board; Cytotoxicity;

机译：类似物;四氢呋喃;酒精饮料控制板;细胞毒性;

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1. ABC synthesis and antitumor activity of a series of Annonaceous acetogenin analogs with a threo, trans, threo, trans, threo-bis-tetrahydrofuran core unit. [J] . Marshall JA, Sabatini JJ, Valeriote F Bioorganic and Medicinal Chemistry Letters . 2007,第9期

机译：一系列具有苏式，反式，苏式，反式，苏式-双-四氢呋喃核心单元的Annnonaceous acetogenin类似物的ABC合成和抗肿瘤活性。
2. In vitro antitumor structure-activity relationships of threo/trans/threo/trans/erythro bis-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I. [J] . Tormo JR, DePedro N, Royo I, Oncology Research . 2005,第3期

机译：苏式/反式/苏式/反式/赤型双-四氢呋喃产乙酸原素的体外抗肿瘤结构-活性关系：与线粒体复合物I的抑制作用相关。
3. In vitro antitumor structure-activity relationships of threo/trans/threo mono-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I. [J] . Tormo JR, Royo I, Gallardo T, Oncology Research . 2003,第3期

机译：苏式/反式/苏式单-四氢呋喃产乙酸原素的体外抗肿瘤结构-活性关系：与抑制线粒体复合体I的相关性。
4. Synthesis, Characterization and Cis-trans Isomerization of a Series of Hyperbranched Conjugated PPV [C] . Qingguo He 11th International Symposium of Fine Chemistry and Functional Polymers Jul 28-31, 2001 Hailar, Inner Mongolia, P.R. China . 2001

机译：一系列超支化共轭PPV的合成，表征和顺反异构
5. I. Synthesis of ether linked analogs and SAR studies of Annonaceous acetogenins II. Asymmetric electrophilic halocyclization reactions [D] . Garzan, Atefeh 2012

机译：I.醚连接的类似物的合成和无水产乙酸原素的SAR研究II。不对称亲电卤代反应
6. Stereoselective Synthesis of trans-Olefins by the Copper-Mediated SN2′ Reaction of Vinyl Oxazines with Grignard Reagents. Asymmetric Synthesis of D-threo-Sphingosines [O] . Om V. Singh, Hyunsoo Han -1

机译：乙烯基恶嗪与格氏试剂在铜介导的SN2反应中立体选择性合成反式烯烃。 D-苏式-神经鞘氨醇的不对称合成
7. Synthesis, Characterization and Solution Chemistry of trans-Indazoliumtetrachlorobis(Indazole)Ruthenate(III), a New Anticancer Ruthenium Complex. IR, UV, NMR, HPLC Investigations and Antitumor Activity. Crystal Structures of trans-1-Methyl-Indazoliumtetrachlorobis-(1-Methylindazole)Ruthenate(III) and its Hydrolysis Product trans-Monoaquatrichlorobis-(1-Methylindazole)-Ruthenate(III) [O] . Lipponer, Kari-Georg, Vogel, Ellen, Keppler, Bernhard K. 1996

机译：of的合成，表征与溶液化学。一种新型的反式吲哚四氯双（吲唑）钌（III）钌抗癌复合物。 IR，UV，NMR，HPLC研究和抗肿瘤活性。反式-1-甲基-吲唑四氯双-（1-甲基吲唑）钌的晶体结构（III）及其水解产物反-季铵三氯-（1-甲基吲唑）-钌（III）
8. Stereospecific Trans Radical Addition of DBr to the 2-Butenes Syntheses of Erythro- and Threo-3-Deutero-2-bromobutanes [R] . Philip S. Skell, Richard G. Allen 1959

机译：DBr的立体特异性反式自由基加成红 - 和Threo-3-Deutero-2-bromobutanes的2-丁烯合成

ABC synthesis and antitumor activity of a series of Annonaceous acetogenin analogs with a threo, trans, threo, trans, threo-bis-tetrahydrofuran core unit.

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