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首页> 外文期刊>Journal of feline medicine and surgery >99MTc - DMSA absolute and relative renal uptake in cats: procedure and normal values.
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99MTc - DMSA absolute and relative renal uptake in cats: procedure and normal values.

机译:99M Tc-猫的DMSA绝对和相对肾脏摄取:程序和正常值。

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摘要

In this study we investigated the influence of technical factors (positioning, background (BG) correction and attenuation correction) on qualitative and quantitative (absolute (AU) and relative (RU) uptake) assessment of feline kidneys with 99mtechnetium labelled dimercaptosuccinic acid (99mTc-DMSA). Eleven healthy adult cats were included. Influence of BG and depth correction on quantitative assessment was evaluated. Depth correction was based on the geometric mean method (using dorsal and ventral images) and the use of two standards placed over each individual kidney. Visual evaluation showed superiority of dorsal and ventral over lateral positioning due to increased separation of the kidneys permitting region of interest (ROI) placement without overlap. No apparent influence of BG correction was found for RU. However, AU was systematically overestimated without BG correction. Depth correction did not seem to affect RU in most cases, however, in some cats the differences were not negligible. The values for AU without depth correction were lower compared to depth corrected values.
机译:在这项研究中,我们研究了技术因素(位置,背景(BG)校正和衰减校正)对 99m tech标记的二巯基琥珀酸( 99m Tc-DMSA)。包括十一只健康的成年猫。评估了BG和深度校正对定量评估的影响。深度校正基于几何均值法(使用背侧和腹侧图像)以及在每个肾脏上放置的两个标准。视觉评估显示背侧和腹侧优于侧向定位,这是因为肾脏的分离增加,允许感兴趣区域(ROI)放置而没有重叠。没有发现BG校正对RU有明显影响。但是,如果不进行BG校正,则系统地高估了AU。在大多数情况下,深度校正似乎并不影响RU,但是,在某些猫中,差异是不可忽略的。没有深度校正的AU值比深度校正的值低。

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