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首页> 外文期刊>Journal of Food Science and Nutrition >Reduction of mouse body fats by water extract of Pleurotus ostreatus
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Reduction of mouse body fats by water extract of Pleurotus ostreatus

机译：平菇水提取物减少小鼠体内脂肪

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Body fat-reducing ability of oyster mushroom (Pleurotus ostreatus) water extract (OMWE) was investigated for mice by supplying it drinking water. OMWE (2.95% solid content) was prepared by extracting a low grade of the mushroom at 120 deg C for 10 min. The solid material of OMWE was composed of 65.2 % reducing sugar, 0.23 % crude fat, 0.5% total protein, 1.2% ash and 32.9% others. OMWE was appropriately diluted with drinking water. Seventy two male ICR mice (25+-1 g, 7#approx#8 weeks of age, 6 mice/cage, 18 mice/treatment) housed in polycarbonate cages containing #beta#-chips were adopted in a temperature- and humidity-controlled facility with free access to water and diet. One week later, the mice were subjected to one of the treatments for 36 days: 0 (control), 10, 50 and 100% OMWE. Drinking water with or without OMWE was supplied twice (40 mi each, 80 nd in total) daily per cage. Body weight and feed intake were recorded every three days. At the end of the experiment, mice were sacrificed to determine the chemical composition (fat, protein, ash and water). Body weight of mice treated with OMWE (10, 50 and 100%) at day 36 was 35.9, 35.9 and 35.5 g per mouse, respectively, and not significantly reduced as compared to that (36.5 g/mouse) of control mice. Average body fat of 0, 10, 50 and 100% OMWE-treated mice was 14.3, 13.1, 10.7 and 12.0%, respectively. Body fat reduction by 50% OMWE treatment was 25.2% (p<0.05), relative to control. OMWE did not affect feed intake. The contents of body protein and ash were increased with respect to body fat decrease, while water content was not changed much. These results suggest that OMWE could reduce body fat of the mice without body weight change, giving the best effect by 50% OMWE.
机译：通过提供饮用水，研究了牡蛎蘑菇水提取物（OMWE）对小鼠的体内降脂能力。 OMWE（2.95％的固体含量）是通过在120摄氏度下提取低级蘑菇10分钟来制备的。 OMWE的固体材料由65.2％的还原糖，0.23％的粗脂肪，0.5％的总蛋白，1.2％的灰分和32.9％的其他成分组成。 OMWE用饮用水适当稀释。在温度和湿度-环境下，采用容纳在装有＃beta＃芯片的聚碳酸酯笼中的72只雄性ICR小鼠（25 + -1 g，约7＃8周龄，每笼6只小鼠，每处理18只小鼠）。控制设施，可免费获得水和饮食。一周后，对小鼠进行其中一种治疗，持续36天：0（对照），10％，50％和100％OMWE。每个笼子每天供应两次有或没有OMWE的饮用水（每个40英里，总计80 nd）。每三天记录一次体重和采食量。实验结束时，处死小鼠以确定化学成分（脂肪，蛋白质，灰分和水）。在第36天，用OMWE处理的小鼠（10、50和100％）的体重分别为每只小鼠35.9、35.9和35.5g，与对照小鼠的（36.5g /小鼠）相比没有显着降低。 0、10、50和100％OMWE处理的小鼠的平均体内脂肪分别为14.3％，13.1％，10.7％和12.0％。相对于对照，通过50％OMWE治疗，人体脂肪减少率为25.2％（p <0.05）。 OMWE不影响采食量。人体蛋白质和灰分的含量相对于体内脂肪的减少而增加，而水含量变化不大。这些结果表明，OMWE可以减少小鼠的脂肪而不改变体重，以50％OMWE的效果最好。

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