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首页> 外文期刊>Journal of genetics >The hsraψ05241 allele of the noncoding hsrio gene of Drosophila melanogaster is not responsible for male sterilityas reported earlier
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The hsraψ05241 allele of the noncoding hsrio gene of Drosophila melanogaster is not responsible for male sterilityas reported earlier

机译：果蝇果蝇的非编码hsrio基因的hsraψ05241等位基因与男性不育无关

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摘要

An earlier report from our laboratory (Rajendra et al. 2001) published in this journal claimed that insertion of the P-transposon at -130bp position in the hsru> promoter was responsible for excessive clustering of the omega speckles in cyst cells in testes, which in turn caused the sterility of hsrw05241 homozygous males. The present communication is to report that trie above conclusion was erroneous since the male sterility of the hsrw05241 homozygous males is actually due to a 2nd site mutation ms21, which appears to be a novel gene in the 61B1 region of chromosome 3. Further, the ms21 mutation, but not the P-transposon insertion in the hsrw gene promoter, is associated with clustering of omega speckles in cyst cells.
机译：我们实验室的较早报告（Rajendra等人，2001年）发表在该杂志上，声称在hsru>启动子中-130bp位置插入P-转座子是造成睾丸内囊细胞中欧米茄斑点过度聚集的原因。反过来引起hsrw05241纯合男性的不育。本交流旨在报告上述结论是错误的，因为hsrw05241纯合男性的雄性不育实际上是由于第二个位点突变ms21所致，该位点似乎是3号染色体61B1区的一个新基因。突变，而不是hsrw基因启动子中的P转座子插入，与囊状细胞中欧米茄斑点的聚集有关。

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